Dionex Acclaim Trinity P1 Series 液相色谱柱

Acclaim Trinity P1 Series

Acclaim Trinity P1 is a unique, high-efficiency, silica-based column designed for pharmaceutical applications such as simultaneous separation of pharmaceutical drug substances and their counterions. This new column, based on nanopolymer silica hybrid (NSH) technology, provides multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange. As a result, its selectivity can be easily optimized by adjusting phase buffer concentration, pH, and solvent content concurrently or independently. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

NSH Chromatographic Features

• Multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

Acclaim Trinity P1 Applications

• Active pharmaceutical ingredients (API) and counterions (cations or anions)
• Screening of pharmaceutical counterions. Both UV and evaporative light scattering (ELS) detectors, in series, are required for simultaneous determination of both drug substances and counterions.
• Mixture of acidic and basic drug substances and respective counterions
• Drug substances of acidic, basic, and neutral mixtures
• High throughput analysis following optimization of the selectivity and resolution. The flow rate can then be increased, and the analysis time shortened.

技术参数：

订购信息：

Dionex Acclaim Trinity P1 Series 液相色谱柱

Acclaim Trinity P1 Series

Acclaim Trinity P1 is a unique, high-efficiency, silica-based column designed for pharmaceutical applications such as simultaneous separation of pharmaceutical drug substances and their counterions. This new column, based on nanopolymer silica hybrid (NSH) technology, provides multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange. As a result, its selectivity can be easily optimized by adjusting phase buffer concentration, pH, and solvent content concurrently or independently. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

NSH Chromatographic Features

• Multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

Acclaim Trinity P1 Applications

• Active pharmaceutical ingredients (API) and counterions (cations or anions)
• Screening of pharmaceutical counterions. Both UV and evaporative light scattering (ELS) detectors, in series, are required for simultaneous determination of both drug substances and counterions.
• Mixture of acidic and basic drug substances and respective counterions
• Drug substances of acidic, basic, and neutral mixtures
• High throughput analysis following optimization of the selectivity and resolution. The flow rate can then be increased, and the analysis time shortened.

技术参数：

订购信息：

Dionex Acclaim Trinity P1 Series 液相色谱柱

Acclaim Trinity P1 Series

Acclaim Trinity P1 is a unique, high-efficiency, silica-based column designed for pharmaceutical applications such as simultaneous separation of pharmaceutical drug substances and their counterions. This new column, based on nanopolymer silica hybrid (NSH) technology, provides multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange. As a result, its selectivity can be easily optimized by adjusting phase buffer concentration, pH, and solvent content concurrently or independently. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

NSH Chromatographic Features

• Multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

Acclaim Trinity P1 Applications

• Active pharmaceutical ingredients (API) and counterions (cations or anions)
• Screening of pharmaceutical counterions. Both UV and evaporative light scattering (ELS) detectors, in series, are required for simultaneous determination of both drug substances and counterions.
• Mixture of acidic and basic drug substances and respective counterions
• Drug substances of acidic, basic, and neutral mixtures
• High throughput analysis following optimization of the selectivity and resolution. The flow rate can then be increased, and the analysis time shortened.

技术参数：

订购信息：

Dionex Acclaim Trinity P1 Series 液相色谱柱

Acclaim Trinity P1 Series

Acclaim Trinity P1 is a unique, high-efficiency, silica-based column designed for pharmaceutical applications such as simultaneous separation of pharmaceutical drug substances and their counterions. This new column, based on nanopolymer silica hybrid (NSH) technology, provides multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange. As a result, its selectivity can be easily optimized by adjusting phase buffer concentration, pH, and solvent content concurrently or independently. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

NSH Chromatographic Features

• Multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

Acclaim Trinity P1 Applications

• Active pharmaceutical ingredients (API) and counterions (cations or anions)
• Screening of pharmaceutical counterions. Both UV and evaporative light scattering (ELS) detectors, in series, are required for simultaneous determination of both drug substances and counterions.
• Mixture of acidic and basic drug substances and respective counterions
• Drug substances of acidic, basic, and neutral mixtures
• High throughput analysis following optimization of the selectivity and resolution. The flow rate can then be increased, and the analysis time shortened.

技术参数：

订购信息：

Dionex Acclaim Trinity P1 Series 液相色谱柱

Acclaim Trinity P1 Series

Acclaim Trinity P1 is a unique, high-efficiency, silica-based column designed for pharmaceutical applications such as simultaneous separation of pharmaceutical drug substances and their counterions. This new column, based on nanopolymer silica hybrid (NSH) technology, provides multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange. As a result, its selectivity can be easily optimized by adjusting phase buffer concentration, pH, and solvent content concurrently or independently. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

NSH Chromatographic Features

• Multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

Acclaim Trinity P1 Applications

• Active pharmaceutical ingredients (API) and counterions (cations or anions)
• Screening of pharmaceutical counterions. Both UV and evaporative light scattering (ELS) detectors, in series, are required for simultaneous determination of both drug substances and counterions.
• Mixture of acidic and basic drug substances and respective counterions
• Drug substances of acidic, basic, and neutral mixtures
• High throughput analysis following optimization of the selectivity and resolution. The flow rate can then be increased, and the analysis time shortened.

技术参数：

订购信息：

Dionex Acclaim Trinity Q1 LC Column 液相色谱柱

Acclaim Trinity Q1 LC Column

Separation of Diquat and Paraquat

Thermo Scientific^? Acclaim^? Trinity^? Q1 columns are unique, high-efficiency, silica-based columns designed for the separation of the herbicides diquat and paraquat. These quaternary amines are widely used as nonselective contact herbicides. Due to their toxicity, they are monitored in drinking water and wastewater for agricultural exposure. The Acclaim Trinity Q1 columns can quickly and easily separate these compounds. The separation is compatible with mass spectrometry detection, which significantly improves sensitivity for the analytes and provides conformation at the same time.

Column features include:

• Excellent resolution of diquat and paraquat
• Good peak shape
• Fast analysis
• LC/MS compatibility
• No ion-pairing reagent needed
• Ease of use

This new column, based on Nanopolymer Silica Hybrid (NSH) technology, provides multiple retention mechanisms, including reversed-phase, anion-exchange, and cation-exchange. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The chromatography can be easily optimized by adjusting phase buffer concentration, pH, and solvent content, concurrently or independently. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

Nano Silica Hybrid (NSH) Chromatographic Features

• Multiple retention mechanisms, including reversed-phase, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagent

技术参数：

订购信息：

Dionex Acclaim Trinity Q1 LC Column 液相色谱柱

Acclaim Trinity Q1 LC Column

Separation of Diquat and Paraquat

Thermo Scientific^? Acclaim^? Trinity^? Q1 columns are unique, high-efficiency, silica-based columns designed for the separation of the herbicides diquat and paraquat. These quaternary amines are widely used as nonselective contact herbicides. Due to their toxicity, they are monitored in drinking water and wastewater for agricultural exposure. The Acclaim Trinity Q1 columns can quickly and easily separate these compounds. The separation is compatible with mass spectrometry detection, which significantly improves sensitivity for the analytes and provides conformation at the same time.

Column features include:

• Excellent resolution of diquat and paraquat
• Good peak shape
• Fast analysis
• LC/MS compatibility
• No ion-pairing reagent needed
• Ease of use

This new column, based on Nanopolymer Silica Hybrid (NSH) technology, provides multiple retention mechanisms, including reversed-phase, anion-exchange, and cation-exchange. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The chromatography can be easily optimized by adjusting phase buffer concentration, pH, and solvent content, concurrently or independently. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

Nano Silica Hybrid (NSH) Chromatographic Features

• Multiple retention mechanisms, including reversed-phase, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagent

技术参数：

订购信息：

Dionex Acclaim Trinity Q1 LC Column 液相色谱柱

Acclaim Trinity Q1 LC Column

Separation of Diquat and Paraquat

Thermo Scientific^? Acclaim^? Trinity^? Q1 columns are unique, high-efficiency, silica-based columns designed for the separation of the herbicides diquat and paraquat. These quaternary amines are widely used as nonselective contact herbicides. Due to their toxicity, they are monitored in drinking water and wastewater for agricultural exposure. The Acclaim Trinity Q1 columns can quickly and easily separate these compounds. The separation is compatible with mass spectrometry detection, which significantly improves sensitivity for the analytes and provides conformation at the same time.

Column features include:

• Excellent resolution of diquat and paraquat
• Good peak shape
• Fast analysis
• LC/MS compatibility
• No ion-pairing reagent needed
• Ease of use

This new column, based on Nanopolymer Silica Hybrid (NSH) technology, provides multiple retention mechanisms, including reversed-phase, anion-exchange, and cation-exchange. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The chromatography can be easily optimized by adjusting phase buffer concentration, pH, and solvent content, concurrently or independently. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

Nano Silica Hybrid (NSH) Chromatographic Features

• Multiple retention mechanisms, including reversed-phase, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagent

技术参数：

订购信息：

Dionex Acclaim Trinity Q1 LC Column 液相色谱柱

Acclaim Trinity Q1 LC Column

Separation of Diquat and Paraquat

Thermo Scientific^? Acclaim^? Trinity^? Q1 columns are unique, high-efficiency, silica-based columns designed for the separation of the herbicides diquat and paraquat. These quaternary amines are widely used as nonselective contact herbicides. Due to their toxicity, they are monitored in drinking water and wastewater for agricultural exposure. The Acclaim Trinity Q1 columns can quickly and easily separate these compounds. The separation is compatible with mass spectrometry detection, which significantly improves sensitivity for the analytes and provides conformation at the same time.

Column features include:

• Excellent resolution of diquat and paraquat
• Good peak shape
• Fast analysis
• LC/MS compatibility
• No ion-pairing reagent needed
• Ease of use

This new column, based on Nanopolymer Silica Hybrid (NSH) technology, provides multiple retention mechanisms, including reversed-phase, anion-exchange, and cation-exchange. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The chromatography can be easily optimized by adjusting phase buffer concentration, pH, and solvent content, concurrently or independently. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

Nano Silica Hybrid (NSH) Chromatographic Features

• Multiple retention mechanisms, including reversed-phase, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagent

技术参数：

订购信息：

Dionex Acclaim Trinity Q1 LC Column 液相色谱柱

Acclaim Trinity Q1 LC Column

Separation of Diquat and Paraquat

Thermo Scientific^? Acclaim^? Trinity^? Q1 columns are unique, high-efficiency, silica-based columns designed for the separation of the herbicides diquat and paraquat. These quaternary amines are widely used as nonselective contact herbicides. Due to their toxicity, they are monitored in drinking water and wastewater for agricultural exposure. The Acclaim Trinity Q1 columns can quickly and easily separate these compounds. The separation is compatible with mass spectrometry detection, which significantly improves sensitivity for the analytes and provides conformation at the same time.

Column features include:

• Excellent resolution of diquat and paraquat
• Good peak shape
• Fast analysis
• LC/MS compatibility
• No ion-pairing reagent needed
• Ease of use

This new column, based on Nanopolymer Silica Hybrid (NSH) technology, provides multiple retention mechanisms, including reversed-phase, anion-exchange, and cation-exchange. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The chromatography can be easily optimized by adjusting phase buffer concentration, pH, and solvent content, concurrently or independently. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

Nano Silica Hybrid (NSH) Chromatographic Features

• Multiple retention mechanisms, including reversed-phase, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagent

技术参数：

订购信息：

Dionex Acclaim 300 C18 Column 生物色谱柱

Acclaim 300 C18 Protein and Peptide Column

High-Resolution Separation of Proteins and Peptides

The Acclaim^? 300 features 3 ?m silica particles for rapid analysis of complex protein digests. The Acclaim 300’s stable bonding make these columns compatible with a wide variety of applications, including LC/MS methods.

• Designed for high-resolution peptide mapping and protein separations
• High-efficiency 3 ?m spherical silica substrate
• High-performance bonding chemistry on 300 ? pore silica
• Application tested for suitablility in peptide mapping
• Reproducible for dependable results
• LC/MS compatible

Manufacture of these columns starts with ultrapure silica that contains minimal concentrations of metal contaminants, minimizing the tailing effects of residual, exposed silanol groups. Exhaustive bonding and end-capping techniques result in stable bonding and columns that exhibit predictable reversed-phase separations with minimal secondary interactions. 

The use of a 3 ?m silica particle reduces limits for diffusion of the analytes into the stationary phase, resulting in fast, high-resolution separations. Compared to 5 ?m column packings, the smaller particles support increased flow rates and shallower gradients on shorter columns, for faster separations. Dionex tests each bonded silica lot for peptide selectivity to ensure reproducible performance.

The standard particle size is nominally 3 ?m. Analytical columns are available in 2.1, 3.0, and 4.6 mm dimeters; standard lengths are 50 and 150 mm. Capillary formats are available in 75 and 300 ?m, 1.0 mm, and custom diameters, and in 50, 150, or 250 mm lengths. Guard columns in both 2.0 and 4.3 mm sizes are recommended to protect analytical columns.

Dionex Acclaim 300 C18 Column 生物色谱柱

Acclaim 300 C18 Protein and Peptide Column

High-Resolution Separation of Proteins and Peptides

The Acclaim^? 300 features 3 ?m silica particles for rapid analysis of complex protein digests. The Acclaim 300’s stable bonding make these columns compatible with a wide variety of applications, including LC/MS methods.

• Designed for high-resolution peptide mapping and protein separations
• High-efficiency 3 ?m spherical silica substrate
• High-performance bonding chemistry on 300 ? pore silica
• Application tested for suitablility in peptide mapping
• Reproducible for dependable results
• LC/MS compatible

Manufacture of these columns starts with ultrapure silica that contains minimal concentrations of metal contaminants, minimizing the tailing effects of residual, exposed silanol groups. Exhaustive bonding and end-capping techniques result in stable bonding and columns that exhibit predictable reversed-phase separations with minimal secondary interactions. 

The use of a 3 ?m silica particle reduces limits for diffusion of the analytes into the stationary phase, resulting in fast, high-resolution separations. Compared to 5 ?m column packings, the smaller particles support increased flow rates and shallower gradients on shorter columns, for faster separations. Dionex tests each bonded silica lot for peptide selectivity to ensure reproducible performance.

The standard particle size is nominally 3 ?m. Analytical columns are available in 2.1, 3.0, and 4.6 mm dimeters; standard lengths are 50 and 150 mm. Capillary formats are available in 75 and 300 ?m, 1.0 mm, and custom diameters, and in 50, 150, or 250 mm lengths. Guard columns in both 2.0 and 4.3 mm sizes are recommended to protect analytical columns.

Dionex Acclaim 300 C18 Column 生物色谱柱

Acclaim 300 C18 Protein and Peptide Column

High-Resolution Separation of Proteins and Peptides

The Acclaim^? 300 features 3 ?m silica particles for rapid analysis of complex protein digests. The Acclaim 300’s stable bonding make these columns compatible with a wide variety of applications, including LC/MS methods.

• Designed for high-resolution peptide mapping and protein separations
• High-efficiency 3 ?m spherical silica substrate
• High-performance bonding chemistry on 300 ? pore silica
• Application tested for suitablility in peptide mapping
• Reproducible for dependable results
• LC/MS compatible

Manufacture of these columns starts with ultrapure silica that contains minimal concentrations of metal contaminants, minimizing the tailing effects of residual, exposed silanol groups. Exhaustive bonding and end-capping techniques result in stable bonding and columns that exhibit predictable reversed-phase separations with minimal secondary interactions. 

The use of a 3 ?m silica particle reduces limits for diffusion of the analytes into the stationary phase, resulting in fast, high-resolution separations. Compared to 5 ?m column packings, the smaller particles support increased flow rates and shallower gradients on shorter columns, for faster separations. Dionex tests each bonded silica lot for peptide selectivity to ensure reproducible performance.

The standard particle size is nominally 3 ?m. Analytical columns are available in 2.1, 3.0, and 4.6 mm dimeters; standard lengths are 50 and 150 mm. Capillary formats are available in 75 and 300 ?m, 1.0 mm, and custom diameters, and in 50, 150, or 250 mm lengths. Guard columns in both 2.0 and 4.3 mm sizes are recommended to protect analytical columns.

Dionex Acclaim 300 C18 Column 生物色谱柱

Acclaim 300 C18 Protein and Peptide Column

High-Resolution Separation of Proteins and Peptides

The Acclaim^? 300 features 3 ?m silica particles for rapid analysis of complex protein digests. The Acclaim 300’s stable bonding make these columns compatible with a wide variety of applications, including LC/MS methods.

• Designed for high-resolution peptide mapping and protein separations
• High-efficiency 3 ?m spherical silica substrate
• High-performance bonding chemistry on 300 ? pore silica
• Application tested for suitablility in peptide mapping
• Reproducible for dependable results
• LC/MS compatible

Manufacture of these columns starts with ultrapure silica that contains minimal concentrations of metal contaminants, minimizing the tailing effects of residual, exposed silanol groups. Exhaustive bonding and end-capping techniques result in stable bonding and columns that exhibit predictable reversed-phase separations with minimal secondary interactions. 

The use of a 3 ?m silica particle reduces limits for diffusion of the analytes into the stationary phase, resulting in fast, high-resolution separations. Compared to 5 ?m column packings, the smaller particles support increased flow rates and shallower gradients on shorter columns, for faster separations. Dionex tests each bonded silica lot for peptide selectivity to ensure reproducible performance.

The standard particle size is nominally 3 ?m. Analytical columns are available in 2.1, 3.0, and 4.6 mm dimeters; standard lengths are 50 and 150 mm. Capillary formats are available in 75 and 300 ?m, 1.0 mm, and custom diameters, and in 50, 150, or 250 mm lengths. Guard columns in both 2.0 and 4.3 mm sizes are recommended to protect analytical columns.

Dionex Acclaim 300 C18 Column 生物色谱柱

Acclaim 300 C18 Protein and Peptide Column

High-Resolution Separation of Proteins and Peptides

The Acclaim^? 300 features 3 ?m silica particles for rapid analysis of complex protein digests. The Acclaim 300’s stable bonding make these columns compatible with a wide variety of applications, including LC/MS methods.

• Designed for high-resolution peptide mapping and protein separations
• High-efficiency 3 ?m spherical silica substrate
• High-performance bonding chemistry on 300 ? pore silica
• Application tested for suitablility in peptide mapping
• Reproducible for dependable results
• LC/MS compatible

Manufacture of these columns starts with ultrapure silica that contains minimal concentrations of metal contaminants, minimizing the tailing effects of residual, exposed silanol groups. Exhaustive bonding and end-capping techniques result in stable bonding and columns that exhibit predictable reversed-phase separations with minimal secondary interactions. 

The use of a 3 ?m silica particle reduces limits for diffusion of the analytes into the stationary phase, resulting in fast, high-resolution separations. Compared to 5 ?m column packings, the smaller particles support increased flow rates and shallower gradients on shorter columns, for faster separations. Dionex tests each bonded silica lot for peptide selectivity to ensure reproducible performance.

The standard particle size is nominally 3 ?m. Analytical columns are available in 2.1, 3.0, and 4.6 mm dimeters; standard lengths are 50 and 150 mm. Capillary formats are available in 75 and 300 ?m, 1.0 mm, and custom diameters, and in 50, 150, or 250 mm lengths. Guard columns in both 2.0 and 4.3 mm sizes are recommended to protect analytical columns.

Dionex Acclaim 300 C18 Column 生物色谱柱

Acclaim 300 C18 Protein and Peptide Column

High-Resolution Separation of Proteins and Peptides

The Acclaim^? 300 features 3 ?m silica particles for rapid analysis of complex protein digests. The Acclaim 300’s stable bonding make these columns compatible with a wide variety of applications, including LC/MS methods.

• Designed for high-resolution peptide mapping and protein separations
• High-efficiency 3 ?m spherical silica substrate
• High-performance bonding chemistry on 300 ? pore silica
• Application tested for suitablility in peptide mapping
• Reproducible for dependable results
• LC/MS compatible

Manufacture of these columns starts with ultrapure silica that contains minimal concentrations of metal contaminants, minimizing the tailing effects of residual, exposed silanol groups. Exhaustive bonding and end-capping techniques result in stable bonding and columns that exhibit predictable reversed-phase separations with minimal secondary interactions. 

The use of a 3 ?m silica particle reduces limits for diffusion of the analytes into the stationary phase, resulting in fast, high-resolution separations. Compared to 5 ?m column packings, the smaller particles support increased flow rates and shallower gradients on shorter columns, for faster separations. Dionex tests each bonded silica lot for peptide selectivity to ensure reproducible performance.

The standard particle size is nominally 3 ?m. Analytical columns are available in 2.1, 3.0, and 4.6 mm dimeters; standard lengths are 50 and 150 mm. Capillary formats are available in 75 and 300 ?m, 1.0 mm, and custom diameters, and in 50, 150, or 250 mm lengths. Guard columns in both 2.0 and 4.3 mm sizes are recommended to protect analytical columns.

Dionex Acclaim 300 C18 Column 生物色谱柱

Acclaim 300 C18 Protein and Peptide Column

High-Resolution Separation of Proteins and Peptides

The Acclaim^? 300 features 3 ?m silica particles for rapid analysis of complex protein digests. The Acclaim 300’s stable bonding make these columns compatible with a wide variety of applications, including LC/MS methods.

• Designed for high-resolution peptide mapping and protein separations
• High-efficiency 3 ?m spherical silica substrate
• High-performance bonding chemistry on 300 ? pore silica
• Application tested for suitablility in peptide mapping
• Reproducible for dependable results
• LC/MS compatible

Manufacture of these columns starts with ultrapure silica that contains minimal concentrations of metal contaminants, minimizing the tailing effects of residual, exposed silanol groups. Exhaustive bonding and end-capping techniques result in stable bonding and columns that exhibit predictable reversed-phase separations with minimal secondary interactions. 

The use of a 3 ?m silica particle reduces limits for diffusion of the analytes into the stationary phase, resulting in fast, high-resolution separations. Compared to 5 ?m column packings, the smaller particles support increased flow rates and shallower gradients on shorter columns, for faster separations. Dionex tests each bonded silica lot for peptide selectivity to ensure reproducible performance.

The standard particle size is nominally 3 ?m. Analytical columns are available in 2.1, 3.0, and 4.6 mm dimeters; standard lengths are 50 and 150 mm. Capillary formats are available in 75 and 300 ?m, 1.0 mm, and custom diameters, and in 50, 150, or 250 mm lengths. Guard columns in both 2.0 and 4.3 mm sizes are recommended to protect analytical columns.

Dionex Acclaim 300 C18 Column 生物色谱柱

Acclaim 300 C18 Protein and Peptide Column

High-Resolution Separation of Proteins and Peptides

The Acclaim^? 300 features 3 ?m silica particles for rapid analysis of complex protein digests. The Acclaim 300’s stable bonding make these columns compatible with a wide variety of applications, including LC/MS methods.

• Designed for high-resolution peptide mapping and protein separations
• High-efficiency 3 ?m spherical silica substrate
• High-performance bonding chemistry on 300 ? pore silica
• Application tested for suitablility in peptide mapping
• Reproducible for dependable results
• LC/MS compatible

Manufacture of these columns starts with ultrapure silica that contains minimal concentrations of metal contaminants, minimizing the tailing effects of residual, exposed silanol groups. Exhaustive bonding and end-capping techniques result in stable bonding and columns that exhibit predictable reversed-phase separations with minimal secondary interactions. 

The use of a 3 ?m silica particle reduces limits for diffusion of the analytes into the stationary phase, resulting in fast, high-resolution separations. Compared to 5 ?m column packings, the smaller particles support increased flow rates and shallower gradients on shorter columns, for faster separations. Dionex tests each bonded silica lot for peptide selectivity to ensure reproducible performance.

The standard particle size is nominally 3 ?m. Analytical columns are available in 2.1, 3.0, and 4.6 mm dimeters; standard lengths are 50 and 150 mm. Capillary formats are available in 75 and 300 ?m, 1.0 mm, and custom diameters, and in 50, 150, or 250 mm lengths. Guard columns in both 2.0 and 4.3 mm sizes are recommended to protect analytical columns.

Dionex Acclaim 300 C18 Column 生物色谱柱

Acclaim 300 C18 Protein and Peptide Column

High-Resolution Separation of Proteins and Peptides

The Acclaim^? 300 features 3 ?m silica particles for rapid analysis of complex protein digests. The Acclaim 300’s stable bonding make these columns compatible with a wide variety of applications, including LC/MS methods.

• Designed for high-resolution peptide mapping and protein separations
• High-efficiency 3 ?m spherical silica substrate
• High-performance bonding chemistry on 300 ? pore silica
• Application tested for suitablility in peptide mapping
• Reproducible for dependable results
• LC/MS compatible

Manufacture of these columns starts with ultrapure silica that contains minimal concentrations of metal contaminants, minimizing the tailing effects of residual, exposed silanol groups. Exhaustive bonding and end-capping techniques result in stable bonding and columns that exhibit predictable reversed-phase separations with minimal secondary interactions. 

The use of a 3 ?m silica particle reduces limits for diffusion of the analytes into the stationary phase, resulting in fast, high-resolution separations. Compared to 5 ?m column packings, the smaller particles support increased flow rates and shallower gradients on shorter columns, for faster separations. Dionex tests each bonded silica lot for peptide selectivity to ensure reproducible performance.

The standard particle size is nominally 3 ?m. Analytical columns are available in 2.1, 3.0, and 4.6 mm dimeters; standard lengths are 50 and 150 mm. Capillary formats are available in 75 and 300 ?m, 1.0 mm, and custom diameters, and in 50, 150, or 250 mm lengths. Guard columns in both 2.0 and 4.3 mm sizes are recommended to protect analytical columns.

Dionex Acclaim 300 C18 Column 生物色谱柱

Acclaim 300 C18 Protein and Peptide Column

High-Resolution Separation of Proteins and Peptides

The Acclaim^? 300 features 3 ?m silica particles for rapid analysis of complex protein digests. The Acclaim 300’s stable bonding make these columns compatible with a wide variety of applications, including LC/MS methods.

• Designed for high-resolution peptide mapping and protein separations
• High-efficiency 3 ?m spherical silica substrate
• High-performance bonding chemistry on 300 ? pore silica
• Application tested for suitablility in peptide mapping
• Reproducible for dependable results
• LC/MS compatible

Manufacture of these columns starts with ultrapure silica that contains minimal concentrations of metal contaminants, minimizing the tailing effects of residual, exposed silanol groups. Exhaustive bonding and end-capping techniques result in stable bonding and columns that exhibit predictable reversed-phase separations with minimal secondary interactions. 

The use of a 3 ?m silica particle reduces limits for diffusion of the analytes into the stationary phase, resulting in fast, high-resolution separations. Compared to 5 ?m column packings, the smaller particles support increased flow rates and shallower gradients on shorter columns, for faster separations. Dionex tests each bonded silica lot for peptide selectivity to ensure reproducible performance.

The standard particle size is nominally 3 ?m. Analytical columns are available in 2.1, 3.0, and 4.6 mm dimeters; standard lengths are 50 and 150 mm. Capillary formats are available in 75 and 300 ?m, 1.0 mm, and custom diameters, and in 50, 150, or 250 mm lengths. Guard columns in both 2.0 and 4.3 mm sizes are recommended to protect analytical columns.