Dionex Acclaim Carbamate LC Column 液相色谱柱

Acclaim Carbamate LC Column 

The Acclaim Carbamate column is designed for baseline separation of carbamates (N-methylcarbamate and N-methylcarbamoyloxime pesticides) specified in US EPA Method 531.2. Carbamate pesticides are widely used throughout the world. Drinking water and raw surface water is monitored for the presence of carbamate pesticides and related compounds using an established EPA Method 531.2 that uses HPLC with postcolumn derivatization. LC-MS is the method of choice for the ultimate sensitivity.

• Baseline separation of carbamate pesticides specified in US EPA Method 531.2
• Use with either LC/postcolumn derivatization/fluorescence or LC/MS detection.
• Compatible with both binary (methanol/water) and ternary (acetonitrile/methanol/water) phase gradients.
• High efficiency, extremely low column bleed, and rugged column packing

Acclaim Carbamate columns are available in a variety of column formats: The 5 μm, 4.6 × 250 mm column sets the standard for the highest resolution with postcolumn reaction (PCR) and fluorescence detection (FLD); the 3 μm, 4.6 × 150 mm column saves time and increases sample throughput; the 3 μm, 3.0 × 150 mm column saves time and reduces solvent consumption; and the 3 μm, 2.1 × 150 mm column is for LC/MS, to achieve the lowest possible detection limits. Two RSLC, 2.2 μm columns are available for high-resolution, high-throughput separations:  2.1 × 100 mm and 2.1 × 150 mm.

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Dionex Acclaim Carbonyl LC Column 液相色谱柱

Acclaim Carbonyl LC Column 

High Resolution HPLC of Aldehyde and Ketone Contaminants

The Thermo Scientific Acclaim* Carbonyl C18 HPLC columns are designed specifically for superior resolution and high-throughput separation for DNPH derivatives of aldehydes and ketones regulated by the U.S. Environmental Protection Agency (EPA) in methods such as EPA 554, EPA 8315, EPA 1667, EPA TO-11, and by the California Environmental Protection Agency Air Resources Board in method CARB 1004.

• High efficiency for UHPLC performance
• Rugged columns with good lot-to-lot reproducibility
• Proven robust methods

Carbonyl compounds, including low molecular weight aldehydes and ketones, cause environmental and health concerns. Because of their highly volatile and reactive nature, carbonyl compounds are often converted to the dinitrophenylhydrazine (DNPH) derivatives prior to analysis. The Acclaim Carbonyl C18 columns are high-performance reversed-phase columns specifically designed for high throughput and baseline separation of thirteen DNPH derivatives of aldehydes and ketones regulated by CARB Method 1004. In addition, the same chromatographic method can be applied directly to other regulatory methods such as EPA 554, EPA 8315, and EPA TO-11.

The columns are available in three particle sizes:  2.2, 3 and 5?m. Smaller particle sizes provide high peak efficiency for fast analysis. Small internal diameter (i.d.) columns (e.g., 2.1 and 3.0 mm) consume less solvents and produce less chemical waste. For high-throughput application, the 2.1 × 100 mm column format combined with high linear velocity should be considered. When high resolution power is desired, a longer column (2.1 × 150 mm) can be used at an optimal linear velocity to achieve even better resolution.

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Dionex Acclaim Carbonyl LC Column 液相色谱柱

Acclaim Carbonyl LC Column 

High Resolution HPLC of Aldehyde and Ketone Contaminants

The Thermo Scientific Acclaim* Carbonyl C18 HPLC columns are designed specifically for superior resolution and high-throughput separation for DNPH derivatives of aldehydes and ketones regulated by the U.S. Environmental Protection Agency (EPA) in methods such as EPA 554, EPA 8315, EPA 1667, EPA TO-11, and by the California Environmental Protection Agency Air Resources Board in method CARB 1004.

• High efficiency for UHPLC performance
• Rugged columns with good lot-to-lot reproducibility
• Proven robust methods

Carbonyl compounds, including low molecular weight aldehydes and ketones, cause environmental and health concerns. Because of their highly volatile and reactive nature, carbonyl compounds are often converted to the dinitrophenylhydrazine (DNPH) derivatives prior to analysis. The Acclaim Carbonyl C18 columns are high-performance reversed-phase columns specifically designed for high throughput and baseline separation of thirteen DNPH derivatives of aldehydes and ketones regulated by CARB Method 1004. In addition, the same chromatographic method can be applied directly to other regulatory methods such as EPA 554, EPA 8315, and EPA TO-11.

The columns are available in three particle sizes:  2.2, 3 and 5?m. Smaller particle sizes provide high peak efficiency for fast analysis. Small internal diameter (i.d.) columns (e.g., 2.1 and 3.0 mm) consume less solvents and produce less chemical waste. For high-throughput application, the 2.1 × 100 mm column format combined with high linear velocity should be considered. When high resolution power is desired, a longer column (2.1 × 150 mm) can be used at an optimal linear velocity to achieve even better resolution.

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Dionex Acclaim Carbonyl LC Column 液相色谱柱

Acclaim Carbonyl LC Column 

High Resolution HPLC of Aldehyde and Ketone Contaminants

The Thermo Scientific Acclaim* Carbonyl C18 HPLC columns are designed specifically for superior resolution and high-throughput separation for DNPH derivatives of aldehydes and ketones regulated by the U.S. Environmental Protection Agency (EPA) in methods such as EPA 554, EPA 8315, EPA 1667, EPA TO-11, and by the California Environmental Protection Agency Air Resources Board in method CARB 1004.

• High efficiency for UHPLC performance
• Rugged columns with good lot-to-lot reproducibility
• Proven robust methods

Carbonyl compounds, including low molecular weight aldehydes and ketones, cause environmental and health concerns. Because of their highly volatile and reactive nature, carbonyl compounds are often converted to the dinitrophenylhydrazine (DNPH) derivatives prior to analysis. The Acclaim Carbonyl C18 columns are high-performance reversed-phase columns specifically designed for high throughput and baseline separation of thirteen DNPH derivatives of aldehydes and ketones regulated by CARB Method 1004. In addition, the same chromatographic method can be applied directly to other regulatory methods such as EPA 554, EPA 8315, and EPA TO-11.

The columns are available in three particle sizes:  2.2, 3 and 5?m. Smaller particle sizes provide high peak efficiency for fast analysis. Small internal diameter (i.d.) columns (e.g., 2.1 and 3.0 mm) consume less solvents and produce less chemical waste. For high-throughput application, the 2.1 × 100 mm column format combined with high linear velocity should be considered. When high resolution power is desired, a longer column (2.1 × 150 mm) can be used at an optimal linear velocity to achieve even better resolution.

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Dionex Acclaim Carbonyl LC Column 液相色谱柱

Acclaim Carbonyl LC Column 

High Resolution HPLC of Aldehyde and Ketone Contaminants

The Thermo Scientific Acclaim* Carbonyl C18 HPLC columns are designed specifically for superior resolution and high-throughput separation for DNPH derivatives of aldehydes and ketones regulated by the U.S. Environmental Protection Agency (EPA) in methods such as EPA 554, EPA 8315, EPA 1667, EPA TO-11, and by the California Environmental Protection Agency Air Resources Board in method CARB 1004.

• High efficiency for UHPLC performance
• Rugged columns with good lot-to-lot reproducibility
• Proven robust methods

Carbonyl compounds, including low molecular weight aldehydes and ketones, cause environmental and health concerns. Because of their highly volatile and reactive nature, carbonyl compounds are often converted to the dinitrophenylhydrazine (DNPH) derivatives prior to analysis. The Acclaim Carbonyl C18 columns are high-performance reversed-phase columns specifically designed for high throughput and baseline separation of thirteen DNPH derivatives of aldehydes and ketones regulated by CARB Method 1004. In addition, the same chromatographic method can be applied directly to other regulatory methods such as EPA 554, EPA 8315, and EPA TO-11.

The columns are available in three particle sizes:  2.2, 3 and 5?m. Smaller particle sizes provide high peak efficiency for fast analysis. Small internal diameter (i.d.) columns (e.g., 2.1 and 3.0 mm) consume less solvents and produce less chemical waste. For high-throughput application, the 2.1 × 100 mm column format combined with high linear velocity should be considered. When high resolution power is desired, a longer column (2.1 × 150 mm) can be used at an optimal linear velocity to achieve even better resolution.

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订购信息：

Dionex Acclaim Carbonyl LC Column 液相色谱柱

Acclaim Carbonyl LC Column 

High Resolution HPLC of Aldehyde and Ketone Contaminants

The Thermo Scientific Acclaim* Carbonyl C18 HPLC columns are designed specifically for superior resolution and high-throughput separation for DNPH derivatives of aldehydes and ketones regulated by the U.S. Environmental Protection Agency (EPA) in methods such as EPA 554, EPA 8315, EPA 1667, EPA TO-11, and by the California Environmental Protection Agency Air Resources Board in method CARB 1004.

• High efficiency for UHPLC performance
• Rugged columns with good lot-to-lot reproducibility
• Proven robust methods

Carbonyl compounds, including low molecular weight aldehydes and ketones, cause environmental and health concerns. Because of their highly volatile and reactive nature, carbonyl compounds are often converted to the dinitrophenylhydrazine (DNPH) derivatives prior to analysis. The Acclaim Carbonyl C18 columns are high-performance reversed-phase columns specifically designed for high throughput and baseline separation of thirteen DNPH derivatives of aldehydes and ketones regulated by CARB Method 1004. In addition, the same chromatographic method can be applied directly to other regulatory methods such as EPA 554, EPA 8315, and EPA TO-11.

The columns are available in three particle sizes:  2.2, 3 and 5?m. Smaller particle sizes provide high peak efficiency for fast analysis. Small internal diameter (i.d.) columns (e.g., 2.1 and 3.0 mm) consume less solvents and produce less chemical waste. For high-throughput application, the 2.1 × 100 mm column format combined with high linear velocity should be considered. When high resolution power is desired, a longer column (2.1 × 150 mm) can be used at an optimal linear velocity to achieve even better resolution.

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Dionex Acclaim Carbonyl LC Column 液相色谱柱

Acclaim Carbonyl LC Column 

High Resolution HPLC of Aldehyde and Ketone Contaminants

The Thermo Scientific Acclaim* Carbonyl C18 HPLC columns are designed specifically for superior resolution and high-throughput separation for DNPH derivatives of aldehydes and ketones regulated by the U.S. Environmental Protection Agency (EPA) in methods such as EPA 554, EPA 8315, EPA 1667, EPA TO-11, and by the California Environmental Protection Agency Air Resources Board in method CARB 1004.

• High efficiency for UHPLC performance
• Rugged columns with good lot-to-lot reproducibility
• Proven robust methods

Carbonyl compounds, including low molecular weight aldehydes and ketones, cause environmental and health concerns. Because of their highly volatile and reactive nature, carbonyl compounds are often converted to the dinitrophenylhydrazine (DNPH) derivatives prior to analysis. The Acclaim Carbonyl C18 columns are high-performance reversed-phase columns specifically designed for high throughput and baseline separation of thirteen DNPH derivatives of aldehydes and ketones regulated by CARB Method 1004. In addition, the same chromatographic method can be applied directly to other regulatory methods such as EPA 554, EPA 8315, and EPA TO-11.

The columns are available in three particle sizes:  2.2, 3 and 5?m. Smaller particle sizes provide high peak efficiency for fast analysis. Small internal diameter (i.d.) columns (e.g., 2.1 and 3.0 mm) consume less solvents and produce less chemical waste. For high-throughput application, the 2.1 × 100 mm column format combined with high linear velocity should be considered. When high resolution power is desired, a longer column (2.1 × 150 mm) can be used at an optimal linear velocity to achieve even better resolution.

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订购信息：

Dionex Acclaim Carbonyl LC Column 液相色谱柱

Acclaim Carbonyl LC Column 

High Resolution HPLC of Aldehyde and Ketone Contaminants

The Thermo Scientific Acclaim* Carbonyl C18 HPLC columns are designed specifically for superior resolution and high-throughput separation for DNPH derivatives of aldehydes and ketones regulated by the U.S. Environmental Protection Agency (EPA) in methods such as EPA 554, EPA 8315, EPA 1667, EPA TO-11, and by the California Environmental Protection Agency Air Resources Board in method CARB 1004.

• High efficiency for UHPLC performance
• Rugged columns with good lot-to-lot reproducibility
• Proven robust methods

Carbonyl compounds, including low molecular weight aldehydes and ketones, cause environmental and health concerns. Because of their highly volatile and reactive nature, carbonyl compounds are often converted to the dinitrophenylhydrazine (DNPH) derivatives prior to analysis. The Acclaim Carbonyl C18 columns are high-performance reversed-phase columns specifically designed for high throughput and baseline separation of thirteen DNPH derivatives of aldehydes and ketones regulated by CARB Method 1004. In addition, the same chromatographic method can be applied directly to other regulatory methods such as EPA 554, EPA 8315, and EPA TO-11.

The columns are available in three particle sizes:  2.2, 3 and 5?m. Smaller particle sizes provide high peak efficiency for fast analysis. Small internal diameter (i.d.) columns (e.g., 2.1 and 3.0 mm) consume less solvents and produce less chemical waste. For high-throughput application, the 2.1 × 100 mm column format combined with high linear velocity should be considered. When high resolution power is desired, a longer column (2.1 × 150 mm) can be used at an optimal linear velocity to achieve even better resolution.

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订购信息：

Dionex Acclaim Carbonyl LC Column 液相色谱柱

Acclaim Carbonyl LC Column 

High Resolution HPLC of Aldehyde and Ketone Contaminants

The Thermo Scientific Acclaim* Carbonyl C18 HPLC columns are designed specifically for superior resolution and high-throughput separation for DNPH derivatives of aldehydes and ketones regulated by the U.S. Environmental Protection Agency (EPA) in methods such as EPA 554, EPA 8315, EPA 1667, EPA TO-11, and by the California Environmental Protection Agency Air Resources Board in method CARB 1004.

• High efficiency for UHPLC performance
• Rugged columns with good lot-to-lot reproducibility
• Proven robust methods

Carbonyl compounds, including low molecular weight aldehydes and ketones, cause environmental and health concerns. Because of their highly volatile and reactive nature, carbonyl compounds are often converted to the dinitrophenylhydrazine (DNPH) derivatives prior to analysis. The Acclaim Carbonyl C18 columns are high-performance reversed-phase columns specifically designed for high throughput and baseline separation of thirteen DNPH derivatives of aldehydes and ketones regulated by CARB Method 1004. In addition, the same chromatographic method can be applied directly to other regulatory methods such as EPA 554, EPA 8315, and EPA TO-11.

The columns are available in three particle sizes:  2.2, 3 and 5?m. Smaller particle sizes provide high peak efficiency for fast analysis. Small internal diameter (i.d.) columns (e.g., 2.1 and 3.0 mm) consume less solvents and produce less chemical waste. For high-throughput application, the 2.1 × 100 mm column format combined with high linear velocity should be considered. When high resolution power is desired, a longer column (2.1 × 150 mm) can be used at an optimal linear velocity to achieve even better resolution.

技术参数：

订购信息：

Dionex Acclaim Carbonyl LC Column 液相色谱柱

Acclaim Carbonyl LC Column 

High Resolution HPLC of Aldehyde and Ketone Contaminants

The Thermo Scientific Acclaim* Carbonyl C18 HPLC columns are designed specifically for superior resolution and high-throughput separation for DNPH derivatives of aldehydes and ketones regulated by the U.S. Environmental Protection Agency (EPA) in methods such as EPA 554, EPA 8315, EPA 1667, EPA TO-11, and by the California Environmental Protection Agency Air Resources Board in method CARB 1004.

• High efficiency for UHPLC performance
• Rugged columns with good lot-to-lot reproducibility
• Proven robust methods

Carbonyl compounds, including low molecular weight aldehydes and ketones, cause environmental and health concerns. Because of their highly volatile and reactive nature, carbonyl compounds are often converted to the dinitrophenylhydrazine (DNPH) derivatives prior to analysis. The Acclaim Carbonyl C18 columns are high-performance reversed-phase columns specifically designed for high throughput and baseline separation of thirteen DNPH derivatives of aldehydes and ketones regulated by CARB Method 1004. In addition, the same chromatographic method can be applied directly to other regulatory methods such as EPA 554, EPA 8315, and EPA TO-11.

The columns are available in three particle sizes:  2.2, 3 and 5μm. Smaller particle sizes provide high peak efficiency for fast analysis. Small internal diameter (i.d.) columns (e.g., 2.1 and 3.0 mm) consume less solvents and produce less chemical waste. For high-throughput application, the 2.1 × 100 mm column format combined with high linear velocity should be considered. When high resolution power is desired, a longer column (2.1 × 150 mm) can be used at an optimal linear velocity to achieve even better resolution.

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Dionex Acclaim Trinity P2 LC Column 液相色谱柱

Acclaim Trinity P2 LC Column

The Thermo Scientific? Acclaim? Trinity? P2 column is a high-performance, silica-based column specifically designed for separation of pharmaceutical mono- and multi-valent counterions by high-performance liquid chromatography (HPLC). This column was engineered for analytical chemists who need simple, robust, fast, generic methods. The Acclaim Trinity P2 columns provide an effective solution for counterion analysis using one column and one method on a standard HPLC instrument.

? Desired selectivity for pharmaceutical mono- and multi-valent counterion screening
? Retention of ionic and ionizable analytes without using ion-pairing reagents
? Compatibility with charged aerosol and mass spectrometry detection methods
? Easy to use
? Rugged packing

The Acclaim Trinity P2 column is based on nanopolymer silica hybrid (NSH) technology.  It consists of high-purity, porous, 3 ?m particles coated with charged nanopolymer particles: the innerpore area of the silica particles is modified with a covalently bonded hydrophilic layer that provides cation exchange retention, while the outer surface is modified with anion-exchange nanopolymer beads. This chemistry design ensures spatial separation of the anion exchange and cation exchange regions. In addition, its hydrophilic surface makes it useful as a hydrophilic interaction liquid chromatography (HILIC) column. Thus, the Acclaim Trinity P2 column provides cation-exchange, anion-exchange, and HILIC retentions on the same stationary phase.

NSH Chromatographic Features

• Multiple retention mechanisms including HILIC, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

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Dionex Acclaim Trinity P2 LC Column 液相色谱柱

Acclaim Trinity P2 LC Column

The Thermo Scientific? Acclaim? Trinity? P2 column is a high-performance, silica-based column specifically designed for separation of pharmaceutical mono- and multi-valent counterions by high-performance liquid chromatography (HPLC). This column was engineered for analytical chemists who need simple, robust, fast, generic methods. The Acclaim Trinity P2 columns provide an effective solution for counterion analysis using one column and one method on a standard HPLC instrument.

? Desired selectivity for pharmaceutical mono- and multi-valent counterion screening
? Retention of ionic and ionizable analytes without using ion-pairing reagents
? Compatibility with charged aerosol and mass spectrometry detection methods
? Easy to use
? Rugged packing

The Acclaim Trinity P2 column is based on nanopolymer silica hybrid (NSH) technology.  It consists of high-purity, porous, 3 ?m particles coated with charged nanopolymer particles: the innerpore area of the silica particles is modified with a covalently bonded hydrophilic layer that provides cation exchange retention, while the outer surface is modified with anion-exchange nanopolymer beads. This chemistry design ensures spatial separation of the anion exchange and cation exchange regions. In addition, its hydrophilic surface makes it useful as a hydrophilic interaction liquid chromatography (HILIC) column. Thus, the Acclaim Trinity P2 column provides cation-exchange, anion-exchange, and HILIC retentions on the same stationary phase.

NSH Chromatographic Features

• Multiple retention mechanisms including HILIC, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

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Dionex Acclaim Trinity P2 LC Column 液相色谱柱

Acclaim Trinity P2 LC Column

The Thermo Scientific? Acclaim? Trinity? P2 column is a high-performance, silica-based column specifically designed for separation of pharmaceutical mono- and multi-valent counterions by high-performance liquid chromatography (HPLC). This column was engineered for analytical chemists who need simple, robust, fast, generic methods. The Acclaim Trinity P2 columns provide an effective solution for counterion analysis using one column and one method on a standard HPLC instrument.

? Desired selectivity for pharmaceutical mono- and multi-valent counterion screening
? Retention of ionic and ionizable analytes without using ion-pairing reagents
? Compatibility with charged aerosol and mass spectrometry detection methods
? Easy to use
? Rugged packing

The Acclaim Trinity P2 column is based on nanopolymer silica hybrid (NSH) technology.  It consists of high-purity, porous, 3 ?m particles coated with charged nanopolymer particles: the innerpore area of the silica particles is modified with a covalently bonded hydrophilic layer that provides cation exchange retention, while the outer surface is modified with anion-exchange nanopolymer beads. This chemistry design ensures spatial separation of the anion exchange and cation exchange regions. In addition, its hydrophilic surface makes it useful as a hydrophilic interaction liquid chromatography (HILIC) column. Thus, the Acclaim Trinity P2 column provides cation-exchange, anion-exchange, and HILIC retentions on the same stationary phase.

NSH Chromatographic Features

• Multiple retention mechanisms including HILIC, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

技术参数：

订购信息：

Dionex Acclaim Trinity P2 LC Column 液相色谱柱

Acclaim Trinity P2 LC Column

The Thermo Scientific? Acclaim? Trinity? P2 column is a high-performance, silica-based column specifically designed for separation of pharmaceutical mono- and multi-valent counterions by high-performance liquid chromatography (HPLC). This column was engineered for analytical chemists who need simple, robust, fast, generic methods. The Acclaim Trinity P2 columns provide an effective solution for counterion analysis using one column and one method on a standard HPLC instrument.

? Desired selectivity for pharmaceutical mono- and multi-valent counterion screening
? Retention of ionic and ionizable analytes without using ion-pairing reagents
? Compatibility with charged aerosol and mass spectrometry detection methods
? Easy to use
? Rugged packing

The Acclaim Trinity P2 column is based on nanopolymer silica hybrid (NSH) technology.  It consists of high-purity, porous, 3 ?m particles coated with charged nanopolymer particles: the innerpore area of the silica particles is modified with a covalently bonded hydrophilic layer that provides cation exchange retention, while the outer surface is modified with anion-exchange nanopolymer beads. This chemistry design ensures spatial separation of the anion exchange and cation exchange regions. In addition, its hydrophilic surface makes it useful as a hydrophilic interaction liquid chromatography (HILIC) column. Thus, the Acclaim Trinity P2 column provides cation-exchange, anion-exchange, and HILIC retentions on the same stationary phase.

NSH Chromatographic Features

• Multiple retention mechanisms including HILIC, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

技术参数：

订购信息：

Dionex Acclaim Trinity P2 LC Column 液相色谱柱

Acclaim Trinity P2 LC Column

The Thermo Scientific? Acclaim? Trinity? P2 column is a high-performance, silica-based column specifically designed for separation of pharmaceutical mono- and multi-valent counterions by high-performance liquid chromatography (HPLC). This column was engineered for analytical chemists who need simple, robust, fast, generic methods. The Acclaim Trinity P2 columns provide an effective solution for counterion analysis using one column and one method on a standard HPLC instrument.

? Desired selectivity for pharmaceutical mono- and multi-valent counterion screening
? Retention of ionic and ionizable analytes without using ion-pairing reagents
? Compatibility with charged aerosol and mass spectrometry detection methods
? Easy to use
? Rugged packing

The Acclaim Trinity P2 column is based on nanopolymer silica hybrid (NSH) technology.  It consists of high-purity, porous, 3 ?m particles coated with charged nanopolymer particles: the innerpore area of the silica particles is modified with a covalently bonded hydrophilic layer that provides cation exchange retention, while the outer surface is modified with anion-exchange nanopolymer beads. This chemistry design ensures spatial separation of the anion exchange and cation exchange regions. In addition, its hydrophilic surface makes it useful as a hydrophilic interaction liquid chromatography (HILIC) column. Thus, the Acclaim Trinity P2 column provides cation-exchange, anion-exchange, and HILIC retentions on the same stationary phase.

NSH Chromatographic Features

• Multiple retention mechanisms including HILIC, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

技术参数：

订购信息：

Dionex Acclaim Trinity P2 LC Column 液相色谱柱

Acclaim Trinity P2 LC Column

The Thermo Scientific? Acclaim? Trinity? P2 column is a high-performance, silica-based column specifically designed for separation of pharmaceutical mono- and multi-valent counterions by high-performance liquid chromatography (HPLC). This column was engineered for analytical chemists who need simple, robust, fast, generic methods. The Acclaim Trinity P2 columns provide an effective solution for counterion analysis using one column and one method on a standard HPLC instrument.

? Desired selectivity for pharmaceutical mono- and multi-valent counterion screening
? Retention of ionic and ionizable analytes without using ion-pairing reagents
? Compatibility with charged aerosol and mass spectrometry detection methods
? Easy to use
? Rugged packing

The Acclaim Trinity P2 column is based on nanopolymer silica hybrid (NSH) technology.  It consists of high-purity, porous, 3 μm particles coated with charged nanopolymer particles: the innerpore area of the silica particles is modified with a covalently bonded hydrophilic layer that provides cation exchange retention, while the outer surface is modified with anion-exchange nanopolymer beads. This chemistry design ensures spatial separation of the anion exchange and cation exchange regions. In addition, its hydrophilic surface makes it useful as a hydrophilic interaction liquid chromatography (HILIC) column. Thus, the Acclaim Trinity P2 column provides cation-exchange, anion-exchange, and HILIC retentions on the same stationary phase.

NSH Chromatographic Features

• Multiple retention mechanisms including HILIC, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

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订购信息：

Dionex Acclaim Trinity P1 Series 液相色谱柱

Acclaim Trinity P1 Series

Acclaim Trinity P1 is a unique, high-efficiency, silica-based column designed for pharmaceutical applications such as simultaneous separation of pharmaceutical drug substances and their counterions. This new column, based on nanopolymer silica hybrid (NSH) technology, provides multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange. As a result, its selectivity can be easily optimized by adjusting phase buffer concentration, pH, and solvent content concurrently or independently. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

NSH Chromatographic Features

• Multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

Acclaim Trinity P1 Applications

• Active pharmaceutical ingredients (API) and counterions (cations or anions)
• Screening of pharmaceutical counterions. Both UV and evaporative light scattering (ELS) detectors, in series, are required for simultaneous determination of both drug substances and counterions.
• Mixture of acidic and basic drug substances and respective counterions
• Drug substances of acidic, basic, and neutral mixtures
• High throughput analysis following optimization of the selectivity and resolution. The flow rate can then be increased, and the analysis time shortened.

技术参数：

订购信息：

Dionex Acclaim Trinity P1 Series 液相色谱柱

Acclaim Trinity P1 Series

Acclaim Trinity P1 is a unique, high-efficiency, silica-based column designed for pharmaceutical applications such as simultaneous separation of pharmaceutical drug substances and their counterions. This new column, based on nanopolymer silica hybrid (NSH) technology, provides multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange. As a result, its selectivity can be easily optimized by adjusting phase buffer concentration, pH, and solvent content concurrently or independently. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

NSH Chromatographic Features

• Multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

Acclaim Trinity P1 Applications

• Active pharmaceutical ingredients (API) and counterions (cations or anions)
• Screening of pharmaceutical counterions. Both UV and evaporative light scattering (ELS) detectors, in series, are required for simultaneous determination of both drug substances and counterions.
• Mixture of acidic and basic drug substances and respective counterions
• Drug substances of acidic, basic, and neutral mixtures
• High throughput analysis following optimization of the selectivity and resolution. The flow rate can then be increased, and the analysis time shortened.

技术参数：

订购信息：

Dionex Acclaim Trinity P1 Series 液相色谱柱

Acclaim Trinity P1 Series

Acclaim Trinity P1 is a unique, high-efficiency, silica-based column designed for pharmaceutical applications such as simultaneous separation of pharmaceutical drug substances and their counterions. This new column, based on nanopolymer silica hybrid (NSH) technology, provides multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange. As a result, its selectivity can be easily optimized by adjusting phase buffer concentration, pH, and solvent content concurrently or independently. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

NSH Chromatographic Features

• Multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

Acclaim Trinity P1 Applications

• Active pharmaceutical ingredients (API) and counterions (cations or anions)
• Screening of pharmaceutical counterions. Both UV and evaporative light scattering (ELS) detectors, in series, are required for simultaneous determination of both drug substances and counterions.
• Mixture of acidic and basic drug substances and respective counterions
• Drug substances of acidic, basic, and neutral mixtures
• High throughput analysis following optimization of the selectivity and resolution. The flow rate can then be increased, and the analysis time shortened.

技术参数：

订购信息：

Dionex Acclaim Trinity P1 Series 液相色谱柱

Acclaim Trinity P1 Series

Acclaim Trinity P1 is a unique, high-efficiency, silica-based column designed for pharmaceutical applications such as simultaneous separation of pharmaceutical drug substances and their counterions. This new column, based on nanopolymer silica hybrid (NSH) technology, provides multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange. As a result, its selectivity can be easily optimized by adjusting phase buffer concentration, pH, and solvent content concurrently or independently. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

NSH Chromatographic Features

• Multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange
• Adjustable selectivity by phase ionic strength, electrolyte type, pH, and organic solvent
• Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
• Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

Acclaim Trinity P1 Applications

• Active pharmaceutical ingredients (API) and counterions (cations or anions)
• Screening of pharmaceutical counterions. Both UV and evaporative light scattering (ELS) detectors, in series, are required for simultaneous determination of both drug substances and counterions.
• Mixture of acidic and basic drug substances and respective counterions
• Drug substances of acidic, basic, and neutral mixtures
• High throughput analysis following optimization of the selectivity and resolution. The flow rate can then be increased, and the analysis time shortened.

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