Dionex ProPac SCX and WCX Protein Column 生物色谱柱

Strong and Weak Cation-Exchange Columns 

for High-Resolution Separation of Proteins and MAbs

New! The Thermo Scientific ProPac^? SCX column line has expanded to include the next generation ProPac SCX-20 column. This column provides unequalled high resolution of protein variants.

Please also see the Thermo Scientific MAbPac^? SCX-10 column, a strong cation-exchange column designed specifically for high-resolution, high-efficiency analysis of monoclonal antibodies (MAbs) and associated variants. This column is complimentary to the industry-leading ProPac WCX-10 column for monoclonal antibody variant analysis. The MAbPac SCX-10 offers an alternative selectivity and provides higher resolution and efficiency for variant analysis of most monoclonal antibody samples than the ProPac WCX-10 column.

ProPac SCX-10 and WCX-10 strong and weak cation-exchange columns are based on a nonporous core particle that results in high-efficiency peaks and high-resolution separations of protein variants. A hydrophilic layer prevents unwanted secondary interactions. A grafted cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

• Characterization and quality control assessment of monoclonal antibodies and other proteins
• Unequalled resolution
• High-resolution separations with excellent sample recovery
• Unmatched column-to-column and lot-to-lot reproducibility
• Useful for characterization of related protein variants (e.g., deamidation and MAb lysine truncation variants)
• Highly-efficient peaks with excellent sample recovery
• Available in different dimensions and formats for flexibility in method development

The ProPac SCX-10 is a strong cation-exchange column with sulfonate functional groups, and the ProPac WCX-10 column has a carboxylate functional group. Both are based on 10 ?m nonporous, polymeric beads and coated with a proprietary hydrophilic layer.

All ProPac columns are manufactured and tested under the strictest specifications, resulting in unmatched column-to-column and lot-to-lot reproducibility. These columns are available as lot-select packages containing three columns from a single lot or three columns from three different lots, to assist quality control scientists in method validation.

Dionex ProPac SCX and WCX Protein Column 生物色谱柱

Strong and Weak Cation-Exchange Columns 

for High-Resolution Separation of Proteins and MAbs

New! The Thermo Scientific ProPac^? SCX column line has expanded to include the next generation ProPac SCX-20 column. This column provides unequalled high resolution of protein variants.

Please also see the Thermo Scientific MAbPac^? SCX-10 column, a strong cation-exchange column designed specifically for high-resolution, high-efficiency analysis of monoclonal antibodies (MAbs) and associated variants. This column is complimentary to the industry-leading ProPac WCX-10 column for monoclonal antibody variant analysis. The MAbPac SCX-10 offers an alternative selectivity and provides higher resolution and efficiency for variant analysis of most monoclonal antibody samples than the ProPac WCX-10 column.

ProPac SCX-10 and WCX-10 strong and weak cation-exchange columns are based on a nonporous core particle that results in high-efficiency peaks and high-resolution separations of protein variants. A hydrophilic layer prevents unwanted secondary interactions. A grafted cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

• Characterization and quality control assessment of monoclonal antibodies and other proteins
• Unequalled resolution
• High-resolution separations with excellent sample recovery
• Unmatched column-to-column and lot-to-lot reproducibility
• Useful for characterization of related protein variants (e.g., deamidation and MAb lysine truncation variants)
• Highly-efficient peaks with excellent sample recovery
• Available in different dimensions and formats for flexibility in method development

The ProPac SCX-10 is a strong cation-exchange column with sulfonate functional groups, and the ProPac WCX-10 column has a carboxylate functional group. Both are based on 10 ?m nonporous, polymeric beads and coated with a proprietary hydrophilic layer.

All ProPac columns are manufactured and tested under the strictest specifications, resulting in unmatched column-to-column and lot-to-lot reproducibility. These columns are available as lot-select packages containing three columns from a single lot or three columns from three different lots, to assist quality control scientists in method validation.

Dionex ProPac SCX and WCX Protein Column 生物色谱柱

Strong and Weak Cation-Exchange Columns 

for High-Resolution Separation of Proteins and MAbs

New! The Thermo Scientific ProPac^? SCX column line has expanded to include the next generation ProPac SCX-20 column. This column provides unequalled high resolution of protein variants.

Please also see the Thermo Scientific MAbPac^? SCX-10 column, a strong cation-exchange column designed specifically for high-resolution, high-efficiency analysis of monoclonal antibodies (MAbs) and associated variants. This column is complimentary to the industry-leading ProPac WCX-10 column for monoclonal antibody variant analysis. The MAbPac SCX-10 offers an alternative selectivity and provides higher resolution and efficiency for variant analysis of most monoclonal antibody samples than the ProPac WCX-10 column.

ProPac SCX-10 and WCX-10 strong and weak cation-exchange columns are based on a nonporous core particle that results in high-efficiency peaks and high-resolution separations of protein variants. A hydrophilic layer prevents unwanted secondary interactions. A grafted cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

• Characterization and quality control assessment of monoclonal antibodies and other proteins
• Unequalled resolution
• High-resolution separations with excellent sample recovery
• Unmatched column-to-column and lot-to-lot reproducibility
• Useful for characterization of related protein variants (e.g., deamidation and MAb lysine truncation variants)
• Highly-efficient peaks with excellent sample recovery
• Available in different dimensions and formats for flexibility in method development

The ProPac SCX-10 is a strong cation-exchange column with sulfonate functional groups, and the ProPac WCX-10 column has a carboxylate functional group. Both are based on 10 ?m nonporous, polymeric beads and coated with a proprietary hydrophilic layer.

All ProPac columns are manufactured and tested under the strictest specifications, resulting in unmatched column-to-column and lot-to-lot reproducibility. These columns are available as lot-select packages containing three columns from a single lot or three columns from three different lots, to assist quality control scientists in method validation.

Dionex ProPac SCX and WCX Protein Column 生物色谱柱

Strong and Weak Cation-Exchange Columns 

for High-Resolution Separation of Proteins and MAbs

New! The Thermo Scientific ProPac^? SCX column line has expanded to include the next generation ProPac SCX-20 column. This column provides unequalled high resolution of protein variants.

Please also see the Thermo Scientific MAbPac^? SCX-10 column, a strong cation-exchange column designed specifically for high-resolution, high-efficiency analysis of monoclonal antibodies (MAbs) and associated variants. This column is complimentary to the industry-leading ProPac WCX-10 column for monoclonal antibody variant analysis. The MAbPac SCX-10 offers an alternative selectivity and provides higher resolution and efficiency for variant analysis of most monoclonal antibody samples than the ProPac WCX-10 column.

ProPac SCX-10 and WCX-10 strong and weak cation-exchange columns are based on a nonporous core particle that results in high-efficiency peaks and high-resolution separations of protein variants. A hydrophilic layer prevents unwanted secondary interactions. A grafted cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

• Characterization and quality control assessment of monoclonal antibodies and other proteins
• Unequalled resolution
• High-resolution separations with excellent sample recovery
• Unmatched column-to-column and lot-to-lot reproducibility
• Useful for characterization of related protein variants (e.g., deamidation and MAb lysine truncation variants)
• Highly-efficient peaks with excellent sample recovery
• Available in different dimensions and formats for flexibility in method development

The ProPac SCX-10 is a strong cation-exchange column with sulfonate functional groups, and the ProPac WCX-10 column has a carboxylate functional group. Both are based on 10 ?m nonporous, polymeric beads and coated with a proprietary hydrophilic layer.

All ProPac columns are manufactured and tested under the strictest specifications, resulting in unmatched column-to-column and lot-to-lot reproducibility. These columns are available as lot-select packages containing three columns from a single lot or three columns from three different lots, to assist quality control scientists in method validation.

Dionex ProPac SCX and WCX Protein Column 生物色谱柱

Strong and Weak Cation-Exchange Columns 

for High-Resolution Separation of Proteins and MAbs

New! The Thermo Scientific ProPac^? SCX column line has expanded to include the next generation ProPac SCX-20 column. This column provides unequalled high resolution of protein variants.

Please also see the Thermo Scientific MAbPac^? SCX-10 column, a strong cation-exchange column designed specifically for high-resolution, high-efficiency analysis of monoclonal antibodies (MAbs) and associated variants. This column is complimentary to the industry-leading ProPac WCX-10 column for monoclonal antibody variant analysis. The MAbPac SCX-10 offers an alternative selectivity and provides higher resolution and efficiency for variant analysis of most monoclonal antibody samples than the ProPac WCX-10 column.

ProPac SCX-10 and WCX-10 strong and weak cation-exchange columns are based on a nonporous core particle that results in high-efficiency peaks and high-resolution separations of protein variants. A hydrophilic layer prevents unwanted secondary interactions. A grafted cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

• Characterization and quality control assessment of monoclonal antibodies and other proteins
• Unequalled resolution
• High-resolution separations with excellent sample recovery
• Unmatched column-to-column and lot-to-lot reproducibility
• Useful for characterization of related protein variants (e.g., deamidation and MAb lysine truncation variants)
• Highly-efficient peaks with excellent sample recovery
• Available in different dimensions and formats for flexibility in method development

The ProPac SCX-10 is a strong cation-exchange column with sulfonate functional groups, and the ProPac WCX-10 column has a carboxylate functional group. Both are based on 10 ?m nonporous, polymeric beads and coated with a proprietary hydrophilic layer.

All ProPac columns are manufactured and tested under the strictest specifications, resulting in unmatched column-to-column and lot-to-lot reproducibility. These columns are available as lot-select packages containing three columns from a single lot or three columns from three different lots, to assist quality control scientists in method validation.

Aminex® HPLC 柱-糖分析柱|125-0095

Dionex ProPac SCX and WCX Protein Column 生物色谱柱

Strong and Weak Cation-Exchange Columns 

for High-Resolution Separation of Proteins and MAbs

New! The Thermo Scientific ProPac^? SCX column line has expanded to include the next generation ProPac SCX-20 column. This column provides unequalled high resolution of protein variants.

Please also see the Thermo Scientific MAbPac^? SCX-10 column, a strong cation-exchange column designed specifically for high-resolution, high-efficiency analysis of monoclonal antibodies (MAbs) and associated variants. This column is complimentary to the industry-leading ProPac WCX-10 column for monoclonal antibody variant analysis. The MAbPac SCX-10 offers an alternative selectivity and provides higher resolution and efficiency for variant analysis of most monoclonal antibody samples than the ProPac WCX-10 column.

ProPac SCX-10 and WCX-10 strong and weak cation-exchange columns are based on a nonporous core particle that results in high-efficiency peaks and high-resolution separations of protein variants. A hydrophilic layer prevents unwanted secondary interactions. A grafted cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

• Characterization and quality control assessment of monoclonal antibodies and other proteins
• Unequalled resolution
• High-resolution separations with excellent sample recovery
• Unmatched column-to-column and lot-to-lot reproducibility
• Useful for characterization of related protein variants (e.g., deamidation and MAb lysine truncation variants)
• Highly-efficient peaks with excellent sample recovery
• Available in different dimensions and formats for flexibility in method development

The ProPac SCX-10 is a strong cation-exchange column with sulfonate functional groups, and the ProPac WCX-10 column has a carboxylate functional group. Both are based on 10 ?m nonporous, polymeric beads and coated with a proprietary hydrophilic layer.

All ProPac columns are manufactured and tested under the strictest specifications, resulting in unmatched column-to-column and lot-to-lot reproducibility. These columns are available as lot-select packages containing three columns from a single lot or three columns from three different lots, to assist quality control scientists in method validation.

Dionex ProPac SCX and WCX Protein Column 生物色谱柱

Strong and Weak Cation-Exchange Columns 

for High-Resolution Separation of Proteins and MAbs

New! The Thermo Scientific ProPac^? SCX column line has expanded to include the next generation ProPac SCX-20 column. This column provides unequalled high resolution of protein variants.

Please also see the Thermo Scientific MAbPac^? SCX-10 column, a strong cation-exchange column designed specifically for high-resolution, high-efficiency analysis of monoclonal antibodies (MAbs) and associated variants. This column is complimentary to the industry-leading ProPac WCX-10 column for monoclonal antibody variant analysis. The MAbPac SCX-10 offers an alternative selectivity and provides higher resolution and efficiency for variant analysis of most monoclonal antibody samples than the ProPac WCX-10 column.

ProPac SCX-10 and WCX-10 strong and weak cation-exchange columns are based on a nonporous core particle that results in high-efficiency peaks and high-resolution separations of protein variants. A hydrophilic layer prevents unwanted secondary interactions. A grafted cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

• Characterization and quality control assessment of monoclonal antibodies and other proteins
• Unequalled resolution
• High-resolution separations with excellent sample recovery
• Unmatched column-to-column and lot-to-lot reproducibility
• Useful for characterization of related protein variants (e.g., deamidation and MAb lysine truncation variants)
• Highly-efficient peaks with excellent sample recovery
• Available in different dimensions and formats for flexibility in method development

The ProPac SCX-10 is a strong cation-exchange column with sulfonate functional groups, and the ProPac WCX-10 column has a carboxylate functional group. Both are based on 10 ?m nonporous, polymeric beads and coated with a proprietary hydrophilic layer.

All ProPac columns are manufactured and tested under the strictest specifications, resulting in unmatched column-to-column and lot-to-lot reproducibility. These columns are available as lot-select packages containing three columns from a single lot or three columns from three different lots, to assist quality control scientists in method validation.

Dionex ProPac SCX and WCX Protein Column 生物色谱柱

Strong and Weak Cation-Exchange Columns 

for High-Resolution Separation of Proteins and MAbs

New! The Thermo Scientific ProPac^? SCX column line has expanded to include the next generation ProPac SCX-20 column. This column provides unequalled high resolution of protein variants.

Please also see the Thermo Scientific MAbPac^? SCX-10 column, a strong cation-exchange column designed specifically for high-resolution, high-efficiency analysis of monoclonal antibodies (MAbs) and associated variants. This column is complimentary to the industry-leading ProPac WCX-10 column for monoclonal antibody variant analysis. The MAbPac SCX-10 offers an alternative selectivity and provides higher resolution and efficiency for variant analysis of most monoclonal antibody samples than the ProPac WCX-10 column.

ProPac SCX-10 and WCX-10 strong and weak cation-exchange columns are based on a nonporous core particle that results in high-efficiency peaks and high-resolution separations of protein variants. A hydrophilic layer prevents unwanted secondary interactions. A grafted cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

• Characterization and quality control assessment of monoclonal antibodies and other proteins
• Unequalled resolution
• High-resolution separations with excellent sample recovery
• Unmatched column-to-column and lot-to-lot reproducibility
• Useful for characterization of related protein variants (e.g., deamidation and MAb lysine truncation variants)
• Highly-efficient peaks with excellent sample recovery
• Available in different dimensions and formats for flexibility in method development

The ProPac SCX-10 is a strong cation-exchange column with sulfonate functional groups, and the ProPac WCX-10 column has a carboxylate functional group. Both are based on 10 ?m nonporous, polymeric beads and coated with a proprietary hydrophilic layer.

All ProPac columns are manufactured and tested under the strictest specifications, resulting in unmatched column-to-column and lot-to-lot reproducibility. These columns are available as lot-select packages containing three columns from a single lot or three columns from three different lots, to assist quality control scientists in method validation.

Dionex ProPac SCX and WCX Protein Column 生物色谱柱

Strong and Weak Cation-Exchange Columns 

for High-Resolution Separation of Proteins and MAbs

New! The Thermo Scientific ProPac^? SCX column line has expanded to include the next generation ProPac SCX-20 column. This column provides unequalled high resolution of protein variants.

Please also see the Thermo Scientific MAbPac^? SCX-10 column, a strong cation-exchange column designed specifically for high-resolution, high-efficiency analysis of monoclonal antibodies (MAbs) and associated variants. This column is complimentary to the industry-leading ProPac WCX-10 column for monoclonal antibody variant analysis. The MAbPac SCX-10 offers an alternative selectivity and provides higher resolution and efficiency for variant analysis of most monoclonal antibody samples than the ProPac WCX-10 column.

ProPac SCX-10 and WCX-10 strong and weak cation-exchange columns are based on a nonporous core particle that results in high-efficiency peaks and high-resolution separations of protein variants. A hydrophilic layer prevents unwanted secondary interactions. A grafted cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

• Characterization and quality control assessment of monoclonal antibodies and other proteins
• Unequalled resolution
• High-resolution separations with excellent sample recovery
• Unmatched column-to-column and lot-to-lot reproducibility
• Useful for characterization of related protein variants (e.g., deamidation and MAb lysine truncation variants)
• Highly-efficient peaks with excellent sample recovery
• Available in different dimensions and formats for flexibility in method development

The ProPac SCX-10 is a strong cation-exchange column with sulfonate functional groups, and the ProPac WCX-10 column has a carboxylate functional group. Both are based on 10 ?m nonporous, polymeric beads and coated with a proprietary hydrophilic layer.

All ProPac columns are manufactured and tested under the strictest specifications, resulting in unmatched column-to-column and lot-to-lot reproducibility. These columns are available as lot-select packages containing three columns from a single lot or three columns from three different lots, to assist quality control scientists in method validation.

美国戴安Dionex ProPac SCX and WCX 079930 生物色谱柱

Strong and Weak Cation-Exchange Columns 

for High-Resolution Separation of Proteins and MAbs

New! The Thermo Scientific ProPac^? SCX column line has expanded to include the next generation ProPac SCX-20 column. This column provides unequalled high resolution of protein variants.

Please also see the Thermo Scientific MAbPac^? SCX-10 column, a strong cation-exchange column designed specifically for high-resolution, high-efficiency analysis of monoclonal antibodies (MAbs) and associated variants. This column is complimentary to the industry-leading ProPac WCX-10 column for monoclonal antibody variant analysis. The MAbPac SCX-10 offers an alternative selectivity and provides higher resolution and efficiency for variant analysis of most monoclonal antibody samples than the ProPac WCX-10 column.

ProPac SCX-10 and WCX-10 strong and weak cation-exchange columns are based on a nonporous core particle that results in high-efficiency peaks and high-resolution separations of protein variants. A hydrophilic layer prevents unwanted secondary interactions. A grafted cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

• Characterization and quality control assessment of monoclonal antibodies and other proteins
• Unequalled resolution
• High-resolution separations with excellent sample recovery
• Unmatched column-to-column and lot-to-lot reproducibility
• Useful for characterization of related protein variants (e.g., deamidation and MAb lysine truncation variants)
• Highly-efficient peaks with excellent sample recovery
• Available in different dimensions and formats for flexibility in method development

The ProPac SCX-10 is a strong cation-exchange column with sulfonate functional groups, and the ProPac WCX-10 column has a carboxylate functional group. Both are based on 10 μm nonporous, polymeric beads and coated with a proprietary hydrophilic layer.

All ProPac columns are manufactured and tested under the strictest specifications, resulting in unmatched column-to-column and lot-to-lot reproducibility. These columns are available as lot-select packages containing three columns from a single lot or three columns from three different lots, to assist quality control scientists in method validation.

美国戴安 Dionex MAbPac SCX-10 analytical column 075749

MAbPac SCX-10 Columns 

for the High-Resolution Separation and Analysis of Monoclonal Antibody Variants

The Thermo Scientific^? MAbPac^? SCX-10 column line has been expanded to include 3 and 5 μm particle sizes for fast, high-resolution analysis as well as rapid separation (RS) columns for bio-UHPLC separations. These smaller-particle-size columns provide the same high resolution as the 10 μm columns, but with significantly faster analysis time. In addition, salt or pH gradients can be used to provide fast high-resolution, high-throughput analysis of monoclonal antibody (MAb) variant samples.

The MAbPac SCX-10 columns are strong cation-exchange columns designed specifically for the high-resolution, high-efficiency analysis of MAbs and associated variants. The unique nonporous pellicular resin provides exceptionally high resolving power, permitting the separation of MAb variants that differ by as little as one charged residue. Hydrophobic interactions with the resin are eliminated for very efficient peaks.

Features:

? Unequalled high-resolution separations
? Exceptionally high efficiency
? Highest resolution of MAb variants
? Unmatched column-to-column and lot-to-lot reproducibility
? Elimination of hydrophobic interactions
? Ideal for stability testing

The MAbPac resin technology is the basis for the superior performance of MAb variant analysis. The nonporous core particle provides high rates of mass transfer, which results in high-efficiency separations. A hydrophilic layer surrounds the polymeric beads, eliminating hydrophobic interactions between proteins and the resin while contributing to high-efficiency peaks. A proprietary grafted cation-exchange surface provides pH selectivity control, resulting in high-resolution separations. In addition, the MAbPac SCX-10 line of columns provides consistent column-to-column and lot-to-lot reproducibility for MAb variant separation results and is ideal for MAb therapeutic method development and high-throughput screening. 

The MAbPac SCX-10 RS columns are designed for use with the Thermo Scientific^? Dionex^?  UltiMate^? 3000 BioRS system. These columns are packed in bioinert, PEEK-lined, stainless steel column hardware suitable for operation up to 10,000 psi. These columns are higher efficiency, and therefore provide higher-resolution separations.

MAbPac SCX-10 columns are designed to address the regulatory requirements for biopharmaceutical characterization. The consistent manufacturing processes ensure reproducibility in methods development and data analysis.

The MAbPac SCX-10 column is complimentary to the industry-leading Thermo Scientific^? ProPac^? WCX-10 column for MAb variant analysis. The MAbPac SCX-10 column offers alternative selectivity and provides higher resolution and efficiency for variant analysis of most MAb samples than the ProPac WCX-10 column.

New MAbPac SCX Column Kits for Validation Now Available

• Three MAbPac SCX-10, 4 × 250 mm columns from one lot of resin
• Three MAbPac SCX-10, 4 × 250 mm columns, one each from three lots of resin

These MAbPac SCX-10 column kits will facilitate the validation process of MAbPac SCX-10 columns for MAb therapeutics development projects.

The MAbPac SCX-10, 10 μm, 9 × 250 mm column is now available for semipreparative applications of MAb variant separations.

美国戴安 Dionex MAbPac SCX-10 analytical column 074631

MAbPac SCX-10 Columns 

for the High-Resolution Separation and Analysis of Monoclonal Antibody Variants

The Thermo Scientific^? MAbPac^? SCX-10 column line has been expanded to include 3 and 5 μm particle sizes for fast, high-resolution analysis as well as rapid separation (RS) columns for bio-UHPLC separations. These smaller-particle-size columns provide the same high resolution as the 10 μm columns, but with significantly faster analysis time. In addition, salt or pH gradients can be used to provide fast high-resolution, high-throughput analysis of monoclonal antibody (MAb) variant samples.

The MAbPac SCX-10 columns are strong cation-exchange columns designed specifically for the high-resolution, high-efficiency analysis of MAbs and associated variants. The unique nonporous pellicular resin provides exceptionally high resolving power, permitting the separation of MAb variants that differ by as little as one charged residue. Hydrophobic interactions with the resin are eliminated for very efficient peaks.

Features:

? Unequalled high-resolution separations
? Exceptionally high efficiency
? Highest resolution of MAb variants
? Unmatched column-to-column and lot-to-lot reproducibility
? Elimination of hydrophobic interactions
? Ideal for stability testing

The MAbPac resin technology is the basis for the superior performance of MAb variant analysis. The nonporous core particle provides high rates of mass transfer, which results in high-efficiency separations. A hydrophilic layer surrounds the polymeric beads, eliminating hydrophobic interactions between proteins and the resin while contributing to high-efficiency peaks. A proprietary grafted cation-exchange surface provides pH selectivity control, resulting in high-resolution separations. In addition, the MAbPac SCX-10 line of columns provides consistent column-to-column and lot-to-lot reproducibility for MAb variant separation results and is ideal for MAb therapeutic method development and high-throughput screening. 

The MAbPac SCX-10 RS columns are designed for use with the Thermo Scientific^? Dionex^?  UltiMate^? 3000 BioRS system. These columns are packed in bioinert, PEEK-lined, stainless steel column hardware suitable for operation up to 10,000 psi. These columns are higher efficiency, and therefore provide higher-resolution separations.

MAbPac SCX-10 columns are designed to address the regulatory requirements for biopharmaceutical characterization. The consistent manufacturing processes ensure reproducibility in methods development and data analysis.

The MAbPac SCX-10 column is complimentary to the industry-leading Thermo Scientific^? ProPac^? WCX-10 column for MAb variant analysis. The MAbPac SCX-10 column offers alternative selectivity and provides higher resolution and efficiency for variant analysis of most MAb samples than the ProPac WCX-10 column.

New MAbPac SCX Column Kits for Validation Now Available

• Three MAbPac SCX-10, 4 × 250 mm columns from one lot of resin
• Three MAbPac SCX-10, 4 × 250 mm columns, one each from three lots of resin

These MAbPac SCX-10 column kits will facilitate the validation process of MAbPac SCX-10 columns for MAb therapeutics development projects.

The MAbPac SCX-10, 10 μm, 9 × 250 mm column is now available for semipreparative applications of MAb variant separations.

美国戴安 Dionex MAbPac SCX-10 analytical column SP6865

MAbPac SCX-10 Columns 

for the High-Resolution Separation and Analysis of Monoclonal Antibody Variants

The Thermo Scientific^? MAbPac^? SCX-10 column line has been expanded to include 3 and 5 μm particle sizes for fast, high-resolution analysis as well as rapid separation (RS) columns for bio-UHPLC separations. These smaller-particle-size columns provide the same high resolution as the 10 μm columns, but with significantly faster analysis time. In addition, salt or pH gradients can be used to provide fast high-resolution, high-throughput analysis of monoclonal antibody (MAb) variant samples.

The MAbPac SCX-10 columns are strong cation-exchange columns designed specifically for the high-resolution, high-efficiency analysis of MAbs and associated variants. The unique nonporous pellicular resin provides exceptionally high resolving power, permitting the separation of MAb variants that differ by as little as one charged residue. Hydrophobic interactions with the resin are eliminated for very efficient peaks.

Features:

? Unequalled high-resolution separations
? Exceptionally high efficiency
? Highest resolution of MAb variants
? Unmatched column-to-column and lot-to-lot reproducibility
? Elimination of hydrophobic interactions
? Ideal for stability testing

The MAbPac resin technology is the basis for the superior performance of MAb variant analysis. The nonporous core particle provides high rates of mass transfer, which results in high-efficiency separations. A hydrophilic layer surrounds the polymeric beads, eliminating hydrophobic interactions between proteins and the resin while contributing to high-efficiency peaks. A proprietary grafted cation-exchange surface provides pH selectivity control, resulting in high-resolution separations. In addition, the MAbPac SCX-10 line of columns provides consistent column-to-column and lot-to-lot reproducibility for MAb variant separation results and is ideal for MAb therapeutic method development and high-throughput screening. 

The MAbPac SCX-10 RS columns are designed for use with the Thermo Scientific^? Dionex^?  UltiMate^? 3000 BioRS system. These columns are packed in bioinert, PEEK-lined, stainless steel column hardware suitable for operation up to 10,000 psi. These columns are higher efficiency, and therefore provide higher-resolution separations.

MAbPac SCX-10 columns are designed to address the regulatory requirements for biopharmaceutical characterization. The consistent manufacturing processes ensure reproducibility in methods development and data analysis.

The MAbPac SCX-10 column is complimentary to the industry-leading Thermo Scientific^? ProPac^? WCX-10 column for MAb variant analysis. The MAbPac SCX-10 column offers alternative selectivity and provides higher resolution and efficiency for variant analysis of most MAb samples than the ProPac WCX-10 column.

New MAbPac SCX Column Kits for Validation Now Available

• Three MAbPac SCX-10, 4 × 250 mm columns from one lot of resin
• Three MAbPac SCX-10, 4 × 250 mm columns, one each from three lots of resin

These MAbPac SCX-10 column kits will facilitate the validation process of MAbPac SCX-10 columns for MAb therapeutics development projects.

The MAbPac SCX-10, 10 μm, 9 × 250 mm column is now available for semipreparative applications of MAb variant separations.

美国戴安 Dionex MAbPac SCX-10 analytical column SP6864

MAbPac SCX-10 Columns 

for the High-Resolution Separation and Analysis of Monoclonal Antibody Variants

The Thermo Scientific^? MAbPac^? SCX-10 column line has been expanded to include 3 and 5 μm particle sizes for fast, high-resolution analysis as well as rapid separation (RS) columns for bio-UHPLC separations. These smaller-particle-size columns provide the same high resolution as the 10 μm columns, but with significantly faster analysis time. In addition, salt or pH gradients can be used to provide fast high-resolution, high-throughput analysis of monoclonal antibody (MAb) variant samples.

The MAbPac SCX-10 columns are strong cation-exchange columns designed specifically for the high-resolution, high-efficiency analysis of MAbs and associated variants. The unique nonporous pellicular resin provides exceptionally high resolving power, permitting the separation of MAb variants that differ by as little as one charged residue. Hydrophobic interactions with the resin are eliminated for very efficient peaks.

Features:

? Unequalled high-resolution separations
? Exceptionally high efficiency
? Highest resolution of MAb variants
? Unmatched column-to-column and lot-to-lot reproducibility
? Elimination of hydrophobic interactions
? Ideal for stability testing

The MAbPac resin technology is the basis for the superior performance of MAb variant analysis. The nonporous core particle provides high rates of mass transfer, which results in high-efficiency separations. A hydrophilic layer surrounds the polymeric beads, eliminating hydrophobic interactions between proteins and the resin while contributing to high-efficiency peaks. A proprietary grafted cation-exchange surface provides pH selectivity control, resulting in high-resolution separations. In addition, the MAbPac SCX-10 line of columns provides consistent column-to-column and lot-to-lot reproducibility for MAb variant separation results and is ideal for MAb therapeutic method development and high-throughput screening. 

The MAbPac SCX-10 RS columns are designed for use with the Thermo Scientific^? Dionex^?  UltiMate^? 3000 BioRS system. These columns are packed in bioinert, PEEK-lined, stainless steel column hardware suitable for operation up to 10,000 psi. These columns are higher efficiency, and therefore provide higher-resolution separations.

MAbPac SCX-10 columns are designed to address the regulatory requirements for biopharmaceutical characterization. The consistent manufacturing processes ensure reproducibility in methods development and data analysis.

The MAbPac SCX-10 column is complimentary to the industry-leading Thermo Scientific^? ProPac^? WCX-10 column for MAb variant analysis. The MAbPac SCX-10 column offers alternative selectivity and provides higher resolution and efficiency for variant analysis of most MAb samples than the ProPac WCX-10 column.

New MAbPac SCX Column Kits for Validation Now Available

• Three MAbPac SCX-10, 4 × 250 mm columns from one lot of resin
• Three MAbPac SCX-10, 4 × 250 mm columns, one each from three lots of resin

These MAbPac SCX-10 column kits will facilitate the validation process of MAbPac SCX-10 columns for MAb therapeutics development projects.

The MAbPac SCX-10, 10 μm, 9 × 250 mm column is now available for semipreparative applications of MAb variant separations.