Pentafluorophenyl PEG, mPEG-PFP Cat. No. PG1-PFP-10k 10000 Da 100 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Pentafluorophenyl PEG, mPEG-PFP

Cat. No. PG1-PFP-10k Pentafluorophenyl PEG, mPEG-PFP           Cat. No. PG1-PFP-10k     10000 Da    100 mg
Specification 10000 Da
Unit Size 100 mg
Price $385.00

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Description:

Nanocs PFP (pentafluorophenyl) functionalized polyethylene glycol (PEG-PFP) is an amine (-NH2) reactive PEG derivative that can be used to modify molecules with available amine groups. Compared to NHS PEG, PFP PEG has greater reactivity, it can react with both prirmary and secondary amine groups at pH 7~9. Nanocs provides a number of PFP functionalized PEG derivatives that can be used for controlled amine pegylation applications.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Solubility: 10 mg/mL, clear in water, chloroform, DMSO.
  • Purity: >95%

Storage Conditions:

  • Store at -20 0C, desiccate. PFP PEG tends to hydrolyze from moisture. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Methacrylate PEG, mPEG-MAR Cat. No. PG1-MAR-350 350 Da 1 g修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Methacrylate PEG, mPEG-MAR

Cat. No. PG1-MAR-350 Methacrylate PEG, mPEG-MAR           Cat. No. PG1-MAR-350     350 Da    1 g
Specification 350 Da
Unit Size 1 g
Price $385.00

Qty Add to Cart

Description:

Methacrylate functionalized polyethylene glycol (PEG methacrylate) is a reactive PEG derivative that can be used to modify proteins, peptides and other materials via available acrylic groups. It is also a polymerizable PEG that can form biocompatible hydrogel. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Methoxy PEG Aldehyde, mPEG-CH2CHO Cat. No. PG1-AL-5k-1 5000 Da 1 g修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Methoxy PEG Aldehyde, mPEG-CH2CHO

Cat. No. PG1-AL-5k-1 Methoxy PEG Aldehyde, mPEG-CH2CHO           Cat. No. PG1-AL-5k-1     5000 Da    1 g
Specification 5000 Da
Unit Size 1 g
Price $385.00

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PEG Aldehyde Description:

Aldeyde PEG is an amine reactive PEG derivative that can be used to modify biomolecules via available amine groups. The reaction between aldehyde group with ε-amine of lysine residues and the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEG aldehydes react with amine groups at a pH of from 5.5 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups. Aldehyde PEG is a commonly used PEG reagent for n-terminus pegylation in proteins or peptides.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C

Reaction Procedures:

Generally, a 10- to 50-fold molar excess of PEG aldehyde over the amount of amine-containing material results in sufficient conjugation.

Materials Required:

  • Pegylation buffer: Amine-free aqueous buffer, pH 6~8.5.
  • PEG aldehyde stock solution: 100 mg in 1 mL conjugation buffer.
  • Washing solution: Distilled water or any aqueous buffer.

Reaction Steps:

Dissolve targeted materials in pegylation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add PEG aldehyde stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. Allow mixture agitates at room temperature for 2~4 hrs at room temperature or overnight 4 0C. After reaction, C=N bond can be reduced by sodium borohydride. Conjugate can be purified either by size exclusion chromatography or dialysis.

Documents
  • SDS
  • DataSheet

Pentafluorophenyl PEG, mPEG-PFP Cat. No. PG1-PFP-20k 20000 Da 100 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Pentafluorophenyl PEG, mPEG-PFP

Cat. No. PG1-PFP-20k Pentafluorophenyl PEG, mPEG-PFP           Cat. No. PG1-PFP-20k     20000 Da    100 mg
Specification 20000 Da
Unit Size 100 mg
Price $385.00

Qty Add to Cart

Description:

Nanocs PFP (pentafluorophenyl) functionalized polyethylene glycol (PEG-PFP) is an amine (-NH2) reactive PEG derivative that can be used to modify molecules with available amine groups. Compared to NHS PEG, PFP PEG has greater reactivity, it can react with both prirmary and secondary amine groups at pH 7~9. Nanocs provides a number of PFP functionalized PEG derivatives that can be used for controlled amine pegylation applications.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Solubility: 10 mg/mL, clear in water, chloroform, DMSO.
  • Purity: >95%

Storage Conditions:

  • Store at -20 0C, desiccate. PFP PEG tends to hydrolyze from moisture. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Lipoic acid PEG, mPEG-LA Cat. No. PG1-LA-5k 5000 Da 100 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Lipoic acid PEG, mPEG-LA

Cat. No. PG1-LA-5k Lipoic acid PEG, mPEG-LA           Cat. No. PG1-LA-5k     5000 Da    100 mg
Specification 5000 Da
Unit Size 100 mg
Price $325.00

Qty Add to Cart

Description:

Lipoic acid, also known as thioctic acid, is an important bioactive molecule participating in various biological processes. PEG functionalized lipoic acid can be used to bind to metallic particle or film surface with its -S-S-bond. Lipoic acid group has high affinity to metallic surfaces and have been widely used for gold nanoparticles and quantum dots surfaces. PEGylated lipoic acid is water soluble and can be used directly in aqueous buffer.

Physical Properties:

  • Off-yellow solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Methacrylate PEG, mPEG-MAR Cat. No. PG1-MAR-350-5g 350 Da 5 g修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Methacrylate PEG, mPEG-MAR

Cat. No. PG1-MAR-350-5g Methacrylate PEG, mPEG-MAR           Cat. No. PG1-MAR-350-5g     350 Da    5 g
Specification 350 Da
Unit Size 5 g
Price $985.00

Qty Add to Cart

Description:

Methacrylate functionalized polyethylene glycol (PEG methacrylate) is a reactive PEG derivative that can be used to modify proteins, peptides and other materials via available acrylic groups. It is also a polymerizable PEG that can form biocompatible hydrogel. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

DOPE PEG, mPEG-DOPE Cat. No. PG1-DO-5k 5000 Da 50 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DOPE PEG, mPEG-DOPE

Cat. No. PG1-DO-5k
Specification 5000 Da
Unit Size 50 mg
Price $485.00

Qty Add to Cart

Description:

1,2-Dioleoyl-sn-Glycero-3-Phosphoethanolamine (DOPE) conjugated Polyethylene Glycol, DOPE PEG is an unsaturated C18 phospholipid PEG conjugate which has both hydrophilicity and hydrophobility. Pegylated phospholipids are excellent liposome formation materials that can be used for drug delivery, gene transfection and vaccine delivery as well. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drugs. These materials can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Thiol PEG, mPEG-SH Cat. No. PG1-TH-5k-1 5000 Da 1 g修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Thiol PEG, mPEG-SH

Cat. No. PG1-TH-5k-1 Thiol PEG, mPEG-SH           Cat. No. PG1-TH-5k-1     5000 Da    1 g
Specification 5000 Da
Unit Size 1 g
Price $325.00

Qty Add to Cart

Synonym: PEG thiol, mPEG-SH, HS-PEG, Polyethylene glycol thiol, mPEG5000 Thiol, Thiol PEG5000

Description:

Thiol functionalized methoxyl polyethylene glycol, PEG thiol (mPEG-SH) is one of Nanocs monofunctional PEG derivatives that can be used to modify proteins, peptides and other materials. Thiol groups also have high affinity to gold surface and are widely used for gold nanoparticles or gold film modification. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • Form: Solid
  • Color: White
  • Solubility: Soluble in water
  • Functional group: Thiol (-SH)
  • Purity: >95%
  • Applications: Surface modification, bioconjugation

Storage Conditions:

  • Store at -20 0C. Avoid frequent thaw and freeze.

References:

Click here to see hundreds of publications using Nanocs PEGs

Documents
  • SDS
  • DataSheet

Related Products
PG1-TH-2k-1 , Thiol PEG, mPEG-SH
PG1-TH-2k-2 , Thiol PEG, mPEG-SH
PG1-TH-1k , Thiol PEG, mPEG-SH
PG1-TH-10k , Thiol PEG, mPEG-SH
PG1-TH-20k , Thiol PEG, mPEG-SH
PG1-TH-30k , Thiol PEG, mPEG-SH
PG1-TH-40k , Thiol PEG, mPEG-SH
PG1-TH-350 , Thiol PEG, mPEG-SH
PG1-TH-550 , Thiol PEG, mPEG-SH
PG1-TH-750 , Thiol PEG, mPEG-SH
PG1-TH-3k-1 , Thiol PEG, mPEG-SH
GP01-5-20 , Gold Nanoparticles, 5 nm, 0.01% Au

PEG Aldehyde, mPEG-CH2CHO Cat. No. PG1-AL-5k-2 5000 Da 5 g修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

PEG Aldehyde, mPEG-CH2CHO

Cat. No. PG1-AL-5k-2 PEG Aldehyde, mPEG-CH2CHO           Cat. No. PG1-AL-5k-2     5000 Da    5 g
Specification 5000 Da
Unit Size 5 g
Price $785.00

Qty Add to Cart

PEG Aldehyde Description:

Aldeyde PEG is an amine reactive PEG derivative that can be used to modify biomolecules via available amine groups. The reaction between aldehyde group with ε-amine of lysine residues and the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEG aldehydes react with amine groups at a pH of from 5.5 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups. Aldehyde PEG is a commonly used PEG reagent for n-terminus pegylation in proteins or peptides.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C

Reaction Procedures:

Generally, a 10- to 50-fold molar excess of PEG aldehyde over the amount of amine-containing material results in sufficient conjugation.

Materials Required:

  • Pegylation buffer: Amine-free aqueous buffer, pH 6~8.5.
  • PEG aldehyde stock solution: 100 mg in 1 mL conjugation buffer.
  • Washing solution: Distilled water or any aqueous buffer.

Reaction Steps:

Dissolve targeted materials in pegylation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add PEG aldehyde stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. Allow mixture agitates at room temperature for 2~4 hrs at room temperature or overnight 4 0C. After reaction, C=N bond can be reduced by sodium borohydride. Conjugate can be purified either by size exclusion chromatography or dialysis.

Documents
  • SDS
  • DataSheet

Lipoic acid PEG, mPEG-LA Cat. No. PG1-LA-2k 2000 Da 100 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Lipoic acid PEG, mPEG-LA

Cat. No. PG1-LA-2k Lipoic acid PEG, mPEG-LA           Cat. No. PG1-LA-2k     2000 Da    100 mg
Specification 2000 Da
Unit Size 100 mg
Price $325.00

Qty Add to Cart

Description:

Lipoic acid, also known as thioctic acid, is an important bioactive molecule participating in various biological processes. PEG functionalized lipoic acid can be used to bind to metallic particle or film surface with its -S-S-bond. Lipoic acid group has high affinity to metallic surfaces and have been widely used for gold nanoparticles and quantum dots surfaces. PEGylated lipoic acid is water soluble and can be used directly in aqueous buffer.

Physical Properties:

  • Off-yellow solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Methacrylate PEG, mPEG-MAR Cat. No. PG1-MAR-350-10g 350 Da 10 g修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Methacrylate PEG, mPEG-MAR

Cat. No. PG1-MAR-350-10g Methacrylate PEG, mPEG-MAR           Cat. No. PG1-MAR-350-10g     350 Da    10 g
Specification 350 Da
Unit Size 10 g
Price $1,485.00

Qty Add to Cart

Description:

Methacrylate functionalized polyethylene glycol (PEG methacrylate) is a reactive PEG derivative that can be used to modify proteins, peptides and other materials via available acrylic groups. It is also a polymerizable PEG that can form biocompatible hydrogel. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

DOPE PEG, mPEG-DOPE Cat. No. PG1-DO-2k 2000 Da 50 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DOPE PEG, mPEG-DOPE

Cat. No. PG1-DO-2k
Specification 2000 Da
Unit Size 50 mg
Price $485.00

Qty Add to Cart

Description:

1,2-Dioleoyl-sn-Glycero-3-Phosphoethanolamine (DOPE) conjugated Polyethylene Glycol, DOPE PEG is an unsaturated C18 phospholipid PEG conjugate which has both hydrophilicity and hydrophobility. Pegylated phospholipids are excellent liposome formation materials that can be used for drug delivery, gene transfection and vaccine delivery as well. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drugs. These materials can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Thiol PEG, mPEG-SH Cat. No. PG1-TH-5k-2 5000 Da 5 g修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Thiol PEG, mPEG-SH

Cat. No. PG1-TH-5k-2 Thiol PEG, mPEG-SH           Cat. No. PG1-TH-5k-2     5000 Da    5 g
Specification 5000 Da
Unit Size 5 g
Price $885.00

Qty Add to Cart

Description:

Thiol functionalized methoxyl polyethylene glycol, PEG thiol (mPEG-SH) is a monofunctional PEG derivative that can be used to modify proteins, peptides and other materials. Thiol groups also have high affinity to gold surface and are widely used for gold nanoparticles or gold film modification. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccate. Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Related Products
PG1-TH-2k-2 , Thiol PEG, mPEG-SH
PG1-TH-550 , Thiol PEG, mPEG-SH
PG1-TH-750 , Thiol PEG, mPEG-SH
PG1-TH-3k-1 , Thiol PEG, mPEG-SH

PEG Aldehyde, mPEG-CH2CHO Cat. No. PG1-AL-2k 2000 Da 500 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

PEG Aldehyde, mPEG-CH2CHO

Cat. No. PG1-AL-2k PEG Aldehyde, mPEG-CH2CHO           Cat. No. PG1-AL-2k     2000 Da    500 mg
Specification 2000 Da
Unit Size 500 mg
Price $385.00

Qty Add to Cart

PEG Aldehyde Description:

Aldeyde PEG is an amine reactive PEG derivative that can be used to modify biomolecules via available amine groups. The reaction between aldehyde group with ε-amine of lysine residues and the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEG aldehydes react with amine groups at a pH of from 5.5 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups. Aldehyde PEG is a commonly used PEG reagent for n-terminus pegylation in proteins or peptides.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C

Reaction Procedures:

Generally, a 10- to 50-fold molar excess of PEG aldehyde over the amount of amine-containing material results in sufficient conjugation.

Materials Required:

  • Pegylation buffer: Amine-free aqueous buffer, pH 6~8.5.
  • PEG aldehyde stock solution: 100 mg in 1 mL conjugation buffer.
  • Washing solution: Distilled water or any aqueous buffer.

Reaction Steps:

Dissolve targeted materials in pegylation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add PEG aldehyde stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. Allow mixture agitates at room temperature for 2~4 hrs at room temperature or overnight 4 0C. After reaction, C=N bond can be reduced by sodium borohydride. Conjugate can be purified either by size exclusion chromatography or dialysis.

Documents
  • SDS
  • DataSheet

Lipoic acid PEG, mPEG-LA Cat. No. PG1-LA-1k 1000 Da 100 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Lipoic acid PEG, mPEG-LA

Cat. No. PG1-LA-1k Lipoic acid PEG, mPEG-LA           Cat. No. PG1-LA-1k     1000 Da    100 mg
Specification 1000 Da
Unit Size 100 mg
Price $385.00

Qty Add to Cart

Description:

Lipoic acid, also known as thioctic acid, is an important bioactive molecule participating in various biological processes. PEG functionalized lipoic acid can be used to bind to metallic particle or film surface with its -S-S-bond. Lipoic acid group has high affinity to metallic surfaces and have been widely used for gold nanoparticles and quantum dots surfaces. PEGylated lipoic acid is water soluble and can be used directly in aqueous buffer.

Physical Properties:

  • Off-yellow solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Methacrylate PEG, mPEG-MAR Cat. No. PG1-MAR-550 550 Da 1 g修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Methacrylate PEG, mPEG-MAR

Cat. No. PG1-MAR-550 Methacrylate PEG, mPEG-MAR           Cat. No. PG1-MAR-550     550 Da    1 g
Specification 550 Da
Unit Size 1 g
Price $385.00

Qty Add to Cart

Description:

Methacrylate functionalized polyethylene glycol (PEG methacrylate) is a reactive PEG derivative that can be used to modify proteins, peptides and other materials via available acrylic groups. It is also a polymerizable PEG that can form biocompatible hydrogel. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Thiol PEG, mPEG-SH Cat. No. PG1-TH-2k-1 2000 Da 1 g修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Thiol PEG, mPEG-SH

Cat. No. PG1-TH-2k-1 Thiol PEG, mPEG-SH           Cat. No. PG1-TH-2k-1     2000 Da    1 g
Specification 2000 Da
Unit Size 1 g
Price $345.00

Qty Add to Cart

Synonym: PEG thiol, mPEG-SH, HS-PEG, Polyethylene glycol thiol, mPEG2000 SH, Thiol PEG2000

Description:

Thiol functionalized methoxyl polyethylene glycol, PEG thiol (mPEG-SH) is one of Nanocs monofunctional PEG derivatives that can be used to modify proteins, peptides and other materials. Thiol groups also have high affinity to gold surface and are widely used for gold nanoparticles or gold film modification. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • Form: Solid
  • Color: White
  • Solubility: Soluble in water
  • Functional group: Thiol (-SH)
  • Purity: >95%
  • Applications: Surface modification, bioconjugation

Storage Conditions:

  • Store at -20 0C. Avoid frequent thaw and freeze.

References:

Click here to see hundreds of publications using Nanocs PEGs

Documents
  • SDS
  • DataSheet

Related Products
PG1-TH-5k-1 , Thiol PEG, mPEG-SH
PG1-TH-2k-2 , Thiol PEG, mPEG-SH
PG1-TH-550 , Thiol PEG, mPEG-SH
PG1-TH-750 , Thiol PEG, mPEG-SH
PG1-TH-3k-1 , Thiol PEG, mPEG-SH
GP01-20-20 , Gold Nanoparticles, 20 nm, 0.01% Au

PEG Aldehyde, mPEG-CH2CHO Cat. No. PG1-AL-1k 1000 Da 100 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

PEG Aldehyde, mPEG-CH2CHO

Cat. No. PG1-AL-1k PEG Aldehyde, mPEG-CH2CHO           Cat. No. PG1-AL-1k     1000 Da    100 mg
Specification 1000 Da
Unit Size 100 mg
Price $385.00

Qty Add to Cart

PEG Aldehyde Description:

Aldeyde PEG is an amine reactive PEG derivative that can be used to modify biomolecules via available amine groups. The reaction between aldehyde group with ε-amine of lysine residues and the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEG aldehydes react with amine groups at a pH of from 5.5 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups. Aldehyde PEG is a commonly used PEG reagent for n-terminus pegylation in proteins or peptides.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C

Reaction Procedures:

Generally, a 10- to 50-fold molar excess of PEG aldehyde over the amount of amine-containing material results in sufficient conjugation.

Materials Required:

  • Pegylation buffer: Amine-free aqueous buffer, pH 6~8.5.
  • PEG aldehyde stock solution: 100 mg in 1 mL conjugation buffer.
  • Washing solution: Distilled water or any aqueous buffer.

Reaction Steps:

Dissolve targeted materials in pegylation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add PEG aldehyde stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. Allow mixture agitates at room temperature for 2~4 hrs at room temperature or overnight 4 0C. After reaction, C=N bond can be reduced by sodium borohydride. Conjugate can be purified either by size exclusion chromatography or dialysis.

Documents
  • SDS
  • DataSheet

Lipoic acid PEG, mPEG-LA Cat. No. PG1-LA-10k 10000 Da 100 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Lipoic acid PEG, mPEG-LA

Cat. No. PG1-LA-10k Lipoic acid PEG, mPEG-LA           Cat. No. PG1-LA-10k     10000 Da    100 mg
Specification 10000 Da
Unit Size 100 mg
Price $385.00

Qty Add to Cart

Description:

Lipoic acid, also known as thioctic acid, is an important bioactive molecule participating in various biological processes. PEG functionalized lipoic acid can be used to bind to metallic particle or film surface with its -S-S-bond. Lipoic acid group has high affinity to metallic surfaces and have been widely used for gold nanoparticles and quantum dots surfaces. PEGylated lipoic acid is water soluble and can be used directly in aqueous buffer.

Physical Properties:

  • Off-yellow solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Methacrylate PEG, mPEG-MAR Cat. No. PG1-MAR-750 750 Da 1 g修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Methacrylate PEG, mPEG-MAR

Cat. No. PG1-MAR-750 Methacrylate PEG, mPEG-MAR           Cat. No. PG1-MAR-750     750 Da    1 g
Specification 750 Da
Unit Size 1 g
Price $325.00

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Description:

Methacrylate functionalized polyethylene glycol (PEG methacrylate) is a reactive PEG derivative that can be used to modify proteins, peptides and other materials via available acrylic groups. It is also a polymerizable PEG that can form biocompatible hydrogel. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet