BioXcell新品推荐

BioXcell新品推荐

研发背景

8D3单克隆抗体可识别小鼠CD71蛋白,也被称为转铁蛋白受体抗体1TfR1)。CD71分子量大小为170-180kDaII型同型二聚跨膜糖蛋白,该蛋白表达于增殖细胞网状细胞和类红细胞前体等细胞的表面。

 

有研究表明,CD71调节细胞增殖的过程中发挥作用。另外,CD71还通过内吞作用协助运铁蛋白将铁转运到胞内 CD71在恶性肿瘤细胞上大量表达,其表达与癌症进展、进程相关。由于CD71在恶性肿瘤细胞上的高表达产生的细胞内化能力以及铁对癌细胞增殖的必要性使转铁蛋白受体TfR1成为将药物输送到恶性细胞中的关键靶标以及研究热点相关研究结果显示8D3抗体可在体内消耗CD71 +细胞。

 

产品信息:

产品货号

BE0329

产品名称

InVivoMAb anti-mouse CD71 (TfR1)

规格

1mg,5mg,25mg, 50mg,100mg

克隆号

8D3

同种型(Isotype)

Rat Ig2a

免疫原(Immunogen)

Mouse transformed endothelioma cell line t.end1

成分(Formulation)

PBS, pH 7.0

Contains no stabilizers or preservatives

内毒素(Endotoxin)

<2EU/mg (<0.002EU/μg)

Determined by LAL gel clotting assay

纯度(Purity)

>95%

Determined by SDS-PAGE

无菌(Sterility)

0.2 μM filtered

生产(Production)

Purified from tissue culture supernatant in an animal free facility

纯化(Purification)

Protein G

保存(Storage)

The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.

应用(Reported Applications)

in vivo depletion of CD71+ cells

Immunofluorescence

Immunohistochemistry(frozen)

Western blot

 

 

BioXcell品牌代理商

上海金畔生物科技有限公司是BioXcell品牌代理商 ,欢迎访问官网了解更多产品信息和订购。
BioXcell

简要描述:

Bio X Cell是一家创新型生物技术公司,销售和生产用于生物医学研究的高品质,大规格(毫克至克)单克隆抗体。我们所有的抗体都以高纯度和低内毒素水平出售,非常适合于体内临床前研究。

Bio X Cell是一家创新型生物技术公司,销售和生产用于生物医学研究的高品质,大规格(毫克至克)单克隆抗体。我们所有的抗体都以高纯度和低内毒素水平出售,非常适合于体内临床前研究。

 

Bio X Cell, located in the United States near Boston, has been generating monoclonal antibodies for biomedical research since 1997. It is Bio X Cell's commitment to provide the scientific community withhigh quality, low price bulk antibodies for pre-clinicalin-vitro andin-vivoexperiments in animal models. Bio X Cell recognises the stringent quality requirements for such studies and the cost constraints faced my many researchers.

Bio X Cell's antibodies are:

Ultra low in endotoxin

Do not contain azide or other preservatives

Highly pure Free of murine viruses

Tested for protein aggregates

Extremely competitive prices

 

Bio X Cell's selected portfolio of antibodies includes the most relevant and best researched antibodies on the market. Bio X Cell also offers contract production/purification from hybridomas Bulk Monoclonal Antibodies for Research.

产品列表:

BioXcell

BE0000-100MG

InVivoMab anti-mouse CD1d

100 mg

BioXcell

BE0000-5MG

InVivoMab anti-mouse CD1d

5 mg

BioXcell

BE0000-25MG

InVivoMab anti-mouse CD1d

25 mg

BioXcell

BE0000-50MG

InVivoMab anti-mouse CD1d

50 mg

BioXcell

BE0001-1-100MG

InVivoMab anti-mouse CD3ε

100mg

BioXcell

BE0001-1-5MG

InVivoMab anti-mouse CD3ε

5 mg

BioXcell

BE0001-1-25MG

InVivoMab anti-mouse CD3ε

25 mg

BioXcell

BE0001-1-50MG

InVivoMab anti-mouse CD3ε

50 mg

BioXcell

BE0001-1FAB 50MG

InVivoMab anti-mouse CD3ε F(ab')2 fragment

50 mg

BioXcell

BE0001-1FAB 5MG

InVivoMab anti-mouse CD3ε F(ab')2 fragment

5 mg

BioXcell

BE0001-1FAB 10MG

InVivoMab anti-mouse CD3ε F(ab')2 fragment

10 mg

BioXcell

BE0001-1FAB 25MG

InVivoMab anti-mouse CD3ε F(ab')2 fragment

25 mg

BioXcell

BE0001-2-100MG

InVivoMab anti-human CD3

100 mg

BioXcell

BE0001-2-5MG

InVivoMab anti-human CD3

5 mg

BioXcell

BE0001-2-25MG

InVivoMab anti-human CD3

25 mg

BioXcell

BE0001-2-50MG

InVivoMab anti-human CD3

50 mg

BioXcell

BE0002-100MG

InVivoMab anti-mouse CD3

100 mg

BioXcell

BE0002-5MG

InVivoMab anti-mouse CD3

5 mg

BioXcell

BE0002-25MG

InVivoMab anti-mouse CD3

25 mg

BioXcell

BE0002-50MG

InVivoMab anti-mouse CD3

50 mg

BioXcell

BE0003-1-100MG

InVivoMab anti-mouse CD4

100 mg

BioXcell

BE0003-1-5MG

InVivoMab anti-mouse CD4

5 mg

BioXcell

BE0003-1-25MG

InVivoMab anti-mouse CD4

25 mg

BioXcell

BE0003-1-50MG

InVivoMab anti-mouse CD4

50 mg

BioXcell

BE0003-2-100MG

InVivoMab anti-human CD4

100 mg

BioXcell

BE0003-2-50MG

InVivoMab anti-human CD4

50 mg