上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Cholic acid PEG Maleimide
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- SDS
- DataSheet
标签归档：maleimide
Cholic acid PEG Maleimide Cat. No. PG2-CLAML-2k 2000 Da 100 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Cholic acid PEG Maleimide
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- SDS
- DataSheet
Cy5 PEG Maleimide, Cy5-PEG-Mal Cat. No. PG2-MLS5-5k 5000 Da 5 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Cy5 PEG Maleimide, Cy5-PEG-Mal
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Description:
Cy5 labeled polyethylene glycol is a near infrared fluorescent PEG derivative that has a maximum absorption at 650 nm and emission around 670 nm. Cy5 labeled PEG derivative can be easily traced from its blue color and strong fluorescence. Additional functionality allows these fluorescent PEG derivatives to be easily conjugated to other molecule or material surfaces.
Physical Properties:
- Blue or dark blue solid or viscous liquid depends on molecule weight;
- Soluble in regular aqeous solution as well as most organic solvents;
Storage Conditions:
- Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
- SDS
- DataSheet
Cy5 PEG Maleimide, Cy5-PEG-Mal Cat. No. PG2-MLS5-3k 3400 Da 5 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Cy5 PEG Maleimide, Cy5-PEG-Mal
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Description:
Cy5 labeled polyethylene glycol is a near infrared fluorescent PEG derivative that has a maximum absorption at 650 nm and emission around 670 nm. Cy5 labeled PEG derivative can be easily traced from its blue color and strong fluorescence. Additional functionality allows these fluorescent PEG derivatives to be easily conjugated to other molecule or material surfaces.
Physical Properties:
- Blue or dark blue solid or viscous liquid depends on molecule weight;
- Soluble in regular aqeous solution as well as most organic solvents;
Storage Conditions:
- Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
- SDS
- DataSheet
Cy5 PEG Maleimide, Cy5-PEG-Mal Cat. No. PG2-MLS5-2k 2000 Da 5 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Cy5 PEG Maleimide, Cy5-PEG-Mal
|
Description:
Cy5 labeled polyethylene glycol is a near infrared fluorescent PEG derivative that has a maximum absorption at 650 nm and emission around 670 nm. Cy5 labeled PEG derivative can be easily traced from its blue color and strong fluorescence. Additional functionality allows these fluorescent PEG derivatives to be easily conjugated to other molecule or material surfaces.
Physical Properties:
- Blue or dark blue solid or viscous liquid depends on molecule weight;
- Soluble in regular aqeous solution as well as most organic solvents;
Storage Conditions:
- Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
- SDS
- DataSheet
Palmitic acid PEG Maleimide Cat. No. PG2-MLPA-3k 3400 Da 100 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Palmitic acid PEG Maleimide
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Description:
Palmitic acid is a 16 carbon saturated fatty acid lipid with excellent hydrophobicity. PEG modified palmitic acid is an excellent amphilphilic polymer with both hydrophilicity and hydrophobility. Pegylated lipids are excellent liposome formation materials that can be used for drug delivery, gene transfection and vaccine delivery as well. These materials can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.
Physical Properties:
- Off-white/white solid or viscous liquid depends on molecule weight;
- Soluble in regular aqeous solution as well as most organic solvents;
Storage Conditions:
- Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
- SDS
- DataSheet
Palmitic acid PEG Maleimide Cat. No. PG2-MLPA-2k 2000 Da 100 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Palmitic acid PEG Maleimide
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Description:
Palmitic acid is a 16 carbon saturated fatty acid lipid with excellent hydrophobicity. PEG modified palmitic acid is an excellent amphilphilic polymer with both hydrophilicity and hydrophobility. Pegylated lipids are excellent liposome formation materials that can be used for drug delivery, gene transfection and vaccine delivery as well. These materials can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.
Physical Properties:
- Off-white/white solid or viscous liquid depends on molecule weight;
- Soluble in regular aqeous solution as well as most organic solvents;
Storage Conditions:
- Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
- SDS
- DataSheet
Maleimide PEG Maleimide, MAL-PEG-MAL Cat. No. PG2-ML-5k 5000 Da 100 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Maleimide PEG Maleimide, MAL-PEG-MAL
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Description:
Maleimide functionalized polyethylene glycol, Maleimide PEG is a sulfhydryl (thiol/SH) group reactive PEG derivative that can be used to selectively modify protein, peptide or any other surfaces with availablesulfhydryl groups. The reaction between maleimide and thiol proceeds readily at pH 6.5~7.5 to form stable thioether bonds.
Physical Properties:
- Off-white/white solid or viscous liquid depends on molecule weight;
- Soluble in regular aqeous solution as well as most organic solvents;
Storage Conditions:
- Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Reaction Procedures:
Generally, a 10- to 20-fold molar excess of Maleimide PEG over the amount of thiol-containing material results in sufficient conjugation.
Materials Required:
- Pegylation buffer, PBS buffer, pH 7 or other thiol-free buffer at pH 7.
- Maleimide stock solution: 100 mg in 1 mL conjugation buffer.
- Washing solution: Distilled water or any aqueous buffer.
Reaction Steps:
Dissolve targeted materials in conjugation buffer. Estimate the concentration thiol groups on the targeted materials. Add maleimide PEG stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. 10~50 molar excess of PEG maleimide needed for optimal conjugation; Allow mixture agitates at room temperature for 2~4 hours at room temperature or overnight at 4 0C.Conjugate can be purified either by size exclusion chromatography or dialysis.
- SDS
- DataSheet
Maleimide PEG Maleimide, MAL-PEG-MAL Cat. No. PG2-ML-3k 3400 Da 100 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Maleimide PEG Maleimide, MAL-PEG-MAL
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Description:
Maleimide functionalized polyethylene glycol, Maleimide PEG is a sulfhydryl (thiol/SH) group reactive PEG derivative that can be used to selectively modify protein, peptide or any other surfaces with availablesulfhydryl groups. The reaction between maleimide and thiol proceeds readily at pH 6.5~7.5 to form stable thioether bonds.
Physical Properties:
- Off-white/white solid or viscous liquid depends on molecule weight;
- Soluble in regular aqeous solution as well as most organic solvents;
Storage Conditions:
- Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Reaction Procedures:
Generally, a 10- to 20-fold molar excess of Maleimide PEG over the amount of thiol-containing material results in sufficient conjugation.
Materials Required:
- Pegylation buffer, PBS buffer, pH 7 or other thiol-free buffer at pH 7.
- Maleimide stock solution: 100 mg in 1 mL conjugation buffer.
- Washing solution: Distilled water or any aqueous buffer.
Reaction Steps:
Dissolve targeted materials in conjugation buffer. Estimate the concentration thiol groups on the targeted materials. Add maleimide PEG stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. 10~50 molar excess of PEG maleimide needed for optimal conjugation; Allow mixture agitates at room temperature for 2~4 hours at room temperature or overnight at 4 0C.Conjugate can be purified either by size exclusion chromatography or dialysis.
- SDS
- DataSheet
Maleimide PEG Maleimide, MAL-PEG-MAL Cat. No. PG2-ML-2k 2000 Da 100 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Maleimide PEG Maleimide, MAL-PEG-MAL
|
Description:
Maleimide functionalized polyethylene glycol, Maleimide PEG is a sulfhydryl (thiol/SH) group reactive PEG derivative that can be used to selectively modify protein, peptide or any other surfaces with availablesulfhydryl groups. The reaction between maleimide and thiol proceeds readily at pH 6.5~7.5 to form stable thioether bonds.
Physical Properties:
- Off-white/white solid or viscous liquid depends on molecule weight;
- Soluble in regular aqeous solution as well as most organic solvents;
Storage Conditions:
- Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Reaction Procedures:
Generally, a 10- to 20-fold molar excess of Maleimide PEG over the amount of thiol-containing material results in sufficient conjugation.
Materials Required:
- Pegylation buffer, PBS buffer, pH 7 or other thiol-free buffer at pH 7.
- Maleimide stock solution: 100 mg in 1 mL conjugation buffer.
- Washing solution: Distilled water or any aqueous buffer.
Reaction Steps:
Dissolve targeted materials in conjugation buffer. Estimate the concentration thiol groups on the targeted materials. Add maleimide PEG stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. 10~50 molar excess of PEG maleimide needed for optimal conjugation; Allow mixture agitates at room temperature for 2~4 hours at room temperature or overnight at 4 0C.Conjugate can be purified either by size exclusion chromatography or dialysis.
- SDS
- DataSheet
Maleimide PEG Maleimide, MAL-PEG-MAL Cat. No. PG2-ML-10k 10000 Da 100 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Maleimide PEG Maleimide, MAL-PEG-MAL
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Description:
Maleimide functionalized polyethylene glycol, Maleimide PEG is a sulfhydryl (thiol/SH) group reactive PEG derivative that can be used to selectively modify protein, peptide or any other surfaces with availablesulfhydryl groups. The reaction between maleimide and thiol proceeds readily at pH 6.5~7.5 to form stable thioether bonds.
Physical Properties:
- Off-white/white solid or viscous liquid depends on molecule weight;
- Soluble in regular aqeous solution as well as most organic solvents;
Storage Conditions:
- Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Reaction Procedures:
Generally, a 10- to 20-fold molar excess of Maleimide PEG over the amount of thiol-containing material results in sufficient conjugation.
Materials Required:
- Pegylation buffer, PBS buffer, pH 7 or other thiol-free buffer at pH 7.
- Maleimide stock solution: 100 mg in 1 mL conjugation buffer.
- Washing solution: Distilled water or any aqueous buffer.
Reaction Steps:
Dissolve targeted materials in conjugation buffer. Estimate the concentration thiol groups on the targeted materials. Add maleimide PEG stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. 10~50 molar excess of PEG maleimide needed for optimal conjugation; Allow mixture agitates at room temperature for 2~4 hours at room temperature or overnight at 4 0C.Conjugate can be purified either by size exclusion chromatography or dialysis.
- SDS
- DataSheet
Maleimide PEG Maleimide, MAL-PEG-MAL Cat. No. PG2-ML-1k 1000 Da 100 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Maleimide PEG Maleimide, MAL-PEG-MAL
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Description:
Maleimide functionalized polyethylene glycol, Maleimide PEG is a sulfhydryl (thiol/SH) group reactive PEG derivative that can be used to selectively modify protein, peptide or any other surfaces with availablesulfhydryl groups. The reaction between maleimide and thiol proceeds readily at pH 6.5~7.5 to form stable thioether bonds.
Physical Properties:
- Off-white/white solid or viscous liquid depends on molecule weight;
- Soluble in regular aqeous solution as well as most organic solvents;
Storage Conditions:
- Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Reaction Procedures:
Generally, a 10- to 20-fold molar excess of Maleimide PEG over the amount of thiol-containing material results in sufficient conjugation.
Materials Required:
- Pegylation buffer, PBS buffer, pH 7 or other thiol-free buffer at pH 7.
- Maleimide stock solution: 100 mg in 1 mL conjugation buffer.
- Washing solution: Distilled water or any aqueous buffer.
Reaction Steps:
Dissolve targeted materials in conjugation buffer. Estimate the concentration thiol groups on the targeted materials. Add maleimide PEG stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. 10~50 molar excess of PEG maleimide needed for optimal conjugation; Allow mixture agitates at room temperature for 2~4 hours at room temperature or overnight at 4 0C.Conjugate can be purified either by size exclusion chromatography or dialysis.
- SDS
- DataSheet
Desthiobiotin PEG Maleimide Cat. No. PG2-DSBML-5k 5000 Da 5 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Desthiobiotin PEG Maleimide
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Desthiobiotin PEG Maleimide:
Desthiobiotin PEG Maleimide is one of Nanocs’ reactive desthiobiotin PEG crosslinkers that can react with thiol (-SH) groups. Maleimide reacts with thiol/sulfhydryl group at neutral pH quckily and efficiently. Reaction between maleimide and thiol allows conjugation of desthiobiotin tag to proteins, antibodies, peptides or nucleic acids with high efficiency. Desthiobiotin is a modified version of biotin. Compared to biotin, desthiobiotin binds to streptavidin, avidin and other biotin-binding proteins with lower affinity and it can be eluted from binding complex under much milder conditions (i.e., by competitive displacement with regular, free biotin). As such, desthiobiotin reagent is a useful alternative to Biotin for avidin-biotin techniques in which nondenaturing elution of the labeled proteins is desired. PEG linker between desthiobiotin and maleimide offers better water solubility, less steric hindrance and enhanced stability.
Physical Properties:
- Off-white/white solid;
- Soluble in water, DMSO or DMF;
- Reactive group: Maleimide;
- Reactive to: Thiol (-SH);
Storage Conditions:
- Store at -20 0C. Desiccate. Avoid frequent thaw and freeze.
- SDS
- DataSheet
Tags: Desthiobiotin PEG,
Maleimide PEG Maleimide, MAL-PEG-MAL Cat. No. PG2-ML-400 400 Da 100 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Maleimide PEG Maleimide, MAL-PEG-MAL
|
Description:
Maleimide functionalized polyethylene glycol, Maleimide PEG is a sulfhydryl (thiol/SH) group reactive PEG derivative that can be used to selectively modify protein, peptide or any other surfaces with availablesulfhydryl groups. The reaction between maleimide and thiol proceeds readily at pH 6.5~7.5 to form stable thioether bonds.
Physical Properties:
- Off-white/white solid or viscous liquid depends on molecule weight;
- Soluble in regular aqeous solution as well as most organic solvents;
Storage Conditions:
- Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Reaction Procedures:
Generally, a 10- to 20-fold molar excess of Maleimide PEG over the amount of thiol-containing material results in sufficient conjugation.
Materials Required:
- Pegylation buffer, PBS buffer, pH 7 or other thiol-free buffer at pH 7.
- Maleimide stock solution: 100 mg in 1 mL conjugation buffer.
- Washing solution: Distilled water or any aqueous buffer.
Reaction Steps:
Dissolve targeted materials in conjugation buffer. Estimate the concentration thiol groups on the targeted materials. Add maleimide PEG stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. 10~50 molar excess of PEG maleimide needed for optimal conjugation; Allow mixture agitates at room temperature for 2~4 hours at room temperature or overnight at 4 0C.Conjugate can be purified either by size exclusion chromatography or dialysis.
- SDS
- DataSheet
Maleimide PEG Maleimide, MAL-PEG-MAL Cat. No. PG2-ML-600 600 Da 100 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Maleimide PEG Maleimide, MAL-PEG-MAL
|
Description:
Maleimide functionalized polyethylene glycol, Maleimide PEG is a sulfhydryl (thiol/SH) group reactive PEG derivative that can be used to selectively modify protein, peptide or any other surfaces with availablesulfhydryl groups. The reaction between maleimide and thiol proceeds readily at pH 6.5~7.5 to form stable thioether bonds.
Physical Properties:
- Off-white/white solid or viscous liquid depends on molecule weight;
- Soluble in regular aqeous solution as well as most organic solvents;
Storage Conditions:
- Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Reaction Procedures:
Generally, a 10- to 20-fold molar excess of Maleimide PEG over the amount of thiol-containing material results in sufficient conjugation.
Materials Required:
- Pegylation buffer, PBS buffer, pH 7 or other thiol-free buffer at pH 7.
- Maleimide stock solution: 100 mg in 1 mL conjugation buffer.
- Washing solution: Distilled water or any aqueous buffer.
Reaction Steps:
Dissolve targeted materials in conjugation buffer. Estimate the concentration thiol groups on the targeted materials. Add maleimide PEG stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. 10~50 molar excess of PEG maleimide needed for optimal conjugation; Allow mixture agitates at room temperature for 2~4 hours at room temperature or overnight at 4 0C.Conjugate can be purified either by size exclusion chromatography or dialysis.
- SDS
- DataSheet
Maleimide PEG Desthiobiotin Cat. No. PG2-DSBML-3k 3400 Da 5 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Maleimide PEG Desthiobiotin
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Desthiobiotin PEG Maleimide:
Desthiobiotin PEG Maleimide is one of Nanocs’ reactive desthiobiotin PEG crosslinkers that can react with thiol (-SH) groups. Maleimide reacts with thiol/sulfhydryl group at neutral pH quckily and efficiently. Reaction between maleimide and thiol allows conjugation of desthiobiotin tag to proteins, antibodies, peptides or nucleic acids with high efficiency. Desthiobiotin is a modified version of biotin. Compared to biotin, desthiobiotin binds to streptavidin, avidin and other biotin-binding proteins with lower affinity and it can be eluted from binding complex under much milder conditions (i.e., by competitive displacement with regular, free biotin). As such, desthiobiotin reagent is a useful alternative to Biotin for avidin-biotin techniques in which nondenaturing elution of the labeled proteins is desired. PEG linker between desthiobiotin and maleimide offers better water solubility, less steric hindrance and enhanced stability.
Physical Properties:
- Off-white/white solid;
- Soluble in water, DMSO or DMF;
- Reactive group: Maleimide;
- Reactive to: Thiol (-SH);
Storage Conditions:
- Store at -20 0C. Desiccate. Avoid frequent thaw and freeze.
- SDS
- DataSheet
Tags: Desthiobiotin PEG,
Maleimide PEG Maleimide, MAL-PEG-MAL Cat. No. PG2-ML-20k 20000 Da 100 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Maleimide PEG Maleimide, MAL-PEG-MAL
|
Description:
Maleimide functionalized polyethylene glycol, Maleimide PEG is a sulfhydryl (thiol/SH) group reactive PEG derivative that can be used to selectively modify protein, peptide or any other surfaces with availablesulfhydryl groups. The reaction between maleimide and thiol proceeds readily at pH 6.5~7.5 to form stable thioether bonds.
Physical Properties:
- Off-white/white solid or viscous liquid depends on molecule weight;
- Soluble in regular aqeous solution as well as most organic solvents;
Storage Conditions:
- Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Reaction Procedures:
Generally, a 10- to 20-fold molar excess of Maleimide PEG over the amount of thiol-containing material results in sufficient conjugation.
Materials Required:
- Pegylation buffer, PBS buffer, pH 7 or other thiol-free buffer at pH 7.
- Maleimide stock solution: 100 mg in 1 mL conjugation buffer.
- Washing solution: Distilled water or any aqueous buffer.
Reaction Steps:
Dissolve targeted materials in conjugation buffer. Estimate the concentration thiol groups on the targeted materials. Add maleimide PEG stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. 10~50 molar excess of PEG maleimide needed for optimal conjugation; Allow mixture agitates at room temperature for 2~4 hours at room temperature or overnight at 4 0C.Conjugate can be purified either by size exclusion chromatography or dialysis.
- SDS
- DataSheet
Desthiobiotin PEG Maleimide Cat. No. PG2-DSBML-2k 2000 Da 5 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Desthiobiotin PEG Maleimide
|
Desthiobiotin PEG Maleimide:
Desthiobiotin PEG Maleimide is one of Nanocs’ reactive desthiobiotin PEG crosslinkers that can react with thiol (-SH) groups. Maleimide reacts with thiol/sulfhydryl group at neutral pH quckily and efficiently. Reaction between maleimide and thiol allows conjugation of desthiobiotin tag to proteins, antibodies, peptides or nucleic acids with high efficiency. Desthiobiotin is a modified version of biotin. Compared to biotin, desthiobiotin binds to streptavidin, avidin and other biotin-binding proteins with lower affinity and it can be eluted from binding complex under much milder conditions (i.e., by competitive displacement with regular, free biotin). As such, desthiobiotin reagent is a useful alternative to Biotin for avidin-biotin techniques in which nondenaturing elution of the labeled proteins is desired. PEG linker between desthiobiotin and maleimide offers better water solubility, less steric hindrance and enhanced stability.
Physical Properties:
- Off-white/white solid;
- Soluble in water, DMSO or DMF;
- Reactive group: Maleimide;
- Reactive to: Thiol (-SH);
Storage Conditions:
- Store at -20 0C. Desiccate. Avoid frequent thaw and freeze.
- SDS
- DataSheet
| PG2-AMDSB-5k , Desthiobiotin PEG amine |
Tags: Desthiobiotin PEG,
Maleimide PEG Maleimide, MAL-PEG-MAL Cat. No. PG2-ML-35k 35000 Da 100 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Maleimide PEG Maleimide, MAL-PEG-MAL
|
Description:
Maleimide functionalized polyethylene glycol, Maleimide PEG is a sulfhydryl (thiol/SH) group reactive PEG derivative that can be used to selectively modify protein, peptide or any other surfaces with availablesulfhydryl groups. The reaction between maleimide and thiol proceeds readily at pH 6.5~7.5 to form stable thioether bonds.
Physical Properties:
- Off-white/white solid or viscous liquid depends on molecule weight;
- Soluble in regular aqeous solution as well as most organic solvents;
Storage Conditions:
- Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Reaction Procedures:
Generally, a 10- to 20-fold molar excess of Maleimide PEG over the amount of thiol-containing material results in sufficient conjugation.
Materials Required:
- Pegylation buffer, PBS buffer, pH 7 or other thiol-free buffer at pH 7.
- Maleimide stock solution: 100 mg in 1 mL conjugation buffer.
- Washing solution: Distilled water or any aqueous buffer.
Reaction Steps:
Dissolve targeted materials in conjugation buffer. Estimate the concentration thiol groups on the targeted materials. Add maleimide PEG stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. 10~50 molar excess of PEG maleimide needed for optimal conjugation; Allow mixture agitates at room temperature for 2~4 hours at room temperature or overnight at 4 0C.Conjugate can be purified either by size exclusion chromatography or dialysis.
- SDS
- DataSheet
8 Arm PEG Maleimide Cat. No. PG8A-ML-40k 40000 Da 25 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
8 Arm PEG Maleimide
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Description:
8 arm PEG derivatives have multiple reactive groups that can be used to modify proteins, peptides and other materials via their functional groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces. .
Physical Properties:
- Off-white/white solid or viscous liquid depends on molecule weight;
- Soluble in regular aqeous solution as well as most organic solvents;
Storage Conditions:
- Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
- SDS
- DataSheet