标签归档：spdp

OPSS-PEG-NHS, SPDP-PEG-NHS Cat. No. PG2-NSOS-5k 5000 Da 100 mg修饰性聚乙二醇

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OPSS-PEG-NHS, SPDP-PEG-NHS

Cat. No. PG2-NSOS-5k OPSS-PEG-NHS, SPDP-PEG-NHS Cat. No. PG2-NSOS-5k 5000 Da 100 mg
Specification 5000 Da
Unit Size 100 mg
Price $325.00

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Description:

Ortho-pyridyl disulfide (OPSS) functionalized polyethylene glycol (OPSS PEG) is a thiol (-SH) group reactive PEG derivative that can be used to modify biomolecules or other materials via their available thiol groups. Ortho-pyridyl disulfide reacts with thiol group to form a stable disulfide bond while a thiol pyridyl group is released.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

OPSS-PEG-NHS, NHS-PEG-SPDP Cat. No. PG2-NSOS-3k 3400 Da 100 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

OPSS-PEG-NHS, NHS-PEG-SPDP

Cat. No. PG2-NSOS-3k OPSS-PEG-NHS, NHS-PEG-SPDP Cat. No. PG2-NSOS-3k 3400 Da 100 mg
Specification 3400 Da
Unit Size 100 mg
Price $325.00

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Description:

Ortho-pyridyl disulfide (OPSS) functionalized polyethylene glycol (OPSS PEG) is a thiol (-SH) group reactive PEG derivative that can be used to modify biomolecules or other materials via their available thiol groups. Ortho-pyridyl disulfide reacts with thiol group to form a stable disulfide bond while a thiol pyridyl group is released.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

OPSS-PEG-COOH, SPDP-PEG-COOH Cat. No. PG2-CAOS-3k 3400 Da 100 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

OPSS-PEG-COOH, SPDP-PEG-COOH

Cat. No. PG2-CAOS-3k
Specification 3400 Da
Unit Size 100 mg
Price $325.00

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Description:

Ortho-pyridyl disulfide (OPSS) functionalized polyethylene glycol (OPSS PEG) is a thiol (-SH) group reactive PEG derivative that can be used to modify biomolecules or other materials via their available thiol groups. Ortho-pyridyl disulfide reacts with thiol group to form a stable disulfide bond while a thiol pyridyl group is released.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

OPSS-PEG-Biotin, SPDP-PEG-Biotin Cat. No. PG2-BNOS-3k 3400 Da 100 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

OPSS-PEG-Biotin, SPDP-PEG-Biotin

Cat. No. PG2-BNOS-3k
Specification 3400 Da
Unit Size 100 mg
Price $325.00

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Description:

Ortho-pyridyl disulfide (OPSS) functionalized polyethylene glycol (OPSS PEG) is a thiol (-SH) group reactive PEG derivative that can be used to modify biomolecules or other materials via their available thiol groups. Ortho-pyridyl disulfide reacts with thiol group to form a stable disulfide bond while a thiol pyridyl group is released.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

OPSS-PEG-Biotin, Biotin-PEG-SPDP Cat. No. PG2-BNOS-2k 2000 Da 100 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

OPSS-PEG-Biotin, Biotin-PEG-SPDP

Cat. No. PG2-BNOS-2k
Specification 2000 Da
Unit Size 100 mg
Price $385.00

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Description:

Ortho-pyridyl disulfide (OPSS) functionalized polyethylene glycol (OPSS PEG) is a thiol (-SH) group reactive PEG derivative that can be used to modify biomolecules or other materials via their available thiol groups. Ortho-pyridyl disulfide reacts with thiol group to form a stable disulfide bond while a thiol pyridyl group is released.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

SPDP (Succinimidyl 3-[2-pyridyldithio] propionate) Cat. No. SPD01 20 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

SPDP (Succinimidyl 3-[2-pyridyldithio] propionate)

Cat. No. SPD01 SPDP (Succinimidyl 3-[2-pyridyldithio] propionate) Cat. No. SPD01 20 mg
Specification
Unit Size 20 mg
Price $325.00

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SPDP Crosslinker Description:

Nanocs SnapLinkTM SPDP crosslinker, N–Succinimidyl 3-(2-pyridyldithio) propionic acid, also called N-succinimidyl 3-(2-pyridyldithio)-propionate, or OPSS-NHS, is a short-length crosslinker for amine to sulfhydryl (thiol) conjugation via its NHS-ester and pyridyldithiol reactive groups that form cleavable disulfide bonds with free thiol groups. Nanocs LC-SPDP is a long-length crossliker for amine to sulfhydryl conjugation via its NHS-ester and pyridyldithiol reactive groups that form cleavable disulfide bonds with free thiol groups.

In addition to above hydrophobic SPDP crosslinker, Nanocs also offer water-soluble SPDP crosslinker either with sulfonated NHS (Sulfo-SPDP) or Pegylated SPDP crosslinker, such as our PEG OPSS products. These SPDP crosslinkers are heterobifunctional and thiol cleavable crosslinkers.

SPDP Crosslinker Physical Properties:

  • Appearance: Off-white/white solid;
  • Reactive groups: NHS ester and pyridyldithiol;
  • Reactive towards: amino (amine) and sulfhydryl (thiol) groups;
  • SPDP crosslinker is membrane permeable;
  • Solubility: Soluble in DMF or DMSO;

SPDP Applications:

  • Adding thiol/sulfhydryl groups to proteins, antibodies or other molecules by reacting with amine groups;
  • Reversible crosslinking of proteins or other molecules;

SPDP Storage Conditions:

  • Store at -20 0C, desicate. Avoid frequent thaw and freeze.
Related Products
PG1-OS-5k , Ortho-pyridine disulfide PEG, mPEG-OPSS

SPDP-Hydrazide (PDPH) Cat. No. PD-HZ-01 25 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

SPDP-Hydrazide (PDPH)

Cat. No. PD-HZ-01
Specification
Unit Size 25 mg
Price $385.00

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SPDP Crosslinker Description:

Nanocs SnapLinkTM SPDP crosslinker, N–Succinimidyl 3-(2-pyridyldithio) propionic acid, also called N-succinimidyl 3-(2-pyridyldithio)-propionate, or OPSS-NHS, is a short-length crosslinker for amine to sulfhydryl (thiol) conjugation via its NHS-ester and pyridyldithiol reactive groups that form cleavable disulfide bonds with free thiol groups. Nanocs LC-SPDP is a long-length crossliker for amine to sulfhydryl conjugation via its NHS-ester and pyridyldithiol reactive groups that form cleavable disulfide bonds with free thiol groups.

In addition to above hydrophobic SPDP crosslinker, Nanocs also offer water-soluble SPDP crosslinker either with sulfonated NHS (Sulfo-SPDP) or Pegylated SPDP crosslinker, such as our PEG OPSS products. These SPDP crosslinkers are heterobifunctional and thiol cleavable crosslinkers.

SPDP Crosslinker Physical Properties:

  • Appearance: Off-white/white solid;
  • Reactive groups: NHS ester and pyridyldithiol;
  • Reactive towards: amino (amine) and sulfhydryl (thiol) groups;
  • SPDP crosslinker is membrane permeable;
  • Solubility: Soluble in DMF or DMSO;

SPDP Applications:

  • Adding thiol/sulfhydryl groups to proteins, antibodies or other molecules by reacting with amine groups;
  • Reversible crosslinking of proteins or other molecules;

SPDP Storage Conditions:

  • Store at -20 0C, desicate. Avoid frequent thaw and freeze.
Related Products
PG1-OS-5k , Ortho-pyridine disulfide PEG, mPEG-OPSS

SPDP; SPDP Crosslinker

发表于由
SPDP; SPDP Crosslinker

SPDP（SPDP交联剂）是一种短链交联剂，用于通过NHS酯和吡啶二硫醇反应性基团与半胱氨酸巯基形成可裂解的（可还原的）二硫键，实现胺与巯基的结合。 它是用于抗体-药物偶联物的谷胱甘肽可切割ADC接头。

产品名称 SPDP; SPDP Crosslinker
中文名称 3-(2-吡啶二硫代)丙酸N-琥珀酰亚胺酯
英文名称 SPDP N-Succinimidyl 3-[2-pyridyldithio]propionate
分子量 312.36
CAS 68181-17-9
分子式 C₁₂H₁₂N₂O₄S₂
存储条件 -20°，避光，惰性气体保护
保存时间 两年

OPSS-PEG-NH2, SPDP PEG amine Cat. No. PG2-AMOS-5k 5000 Da 100 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

OPSS-PEG-NH2, SPDP PEG amine

Cat. No. PG2-AMOS-5k
Specification 5000 Da
Unit Size 100 mg
Price $325.00

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Description:

Ortho-pyridyl disulfide (OPSS) functionalized polyethylene glycol (OPSS PEG) is a thiol (-SH) group reactive PEG derivative that can be used to modify biomolecules or other materials via their available thiol groups. Ortho-pyridyl disulfide reacts with thiol group to form a stable disulfide bond while a thiol pyridyl group is released.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

OPSS-PEG-NH2, SPDP-PEG-NH2 Cat. No. PG2-AMOS-1k 1000 Da 100 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

OPSS-PEG-NH2, SPDP-PEG-NH2

Cat. No. PG2-AMOS-1k
Specification 1000 Da
Unit Size 100 mg
Price $485.00

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Description:

Ortho-pyridyl disulfide (OPSS) functionalized polyethylene glycol (OPSS PEG) is a thiol (-SH) group reactive PEG derivative that can be used to modify biomolecules or other materials via their available thiol groups. Ortho-pyridyl disulfide reacts with thiol group to form a stable disulfide bond while a thiol pyridyl group is released.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

OPSS-PEG-NH2, NH2-PEG-SPDP Cat. No. PG2-AMOS-400 400 Da 100 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

OPSS-PEG-NH2, NH2-PEG-SPDP

Cat. No. PG2-AMOS-400
Specification 400 Da
Unit Size 100 mg
Price $685.00

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Description:

Ortho-pyridyl disulfide (OPSS) functionalized polyethylene glycol (OPSS PEG) is a thiol (-SH) group reactive PEG derivative that can be used to modify biomolecules or other materials via their available thiol groups. Ortho-pyridyl disulfide reacts with thiol group to form a stable disulfide bond while a thiol pyridyl group is released.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

DSPE SPDP Cat. No. DS-PD-1 5 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DSPE SPDP

Cat. No. DS-PD-1
Specification
Unit Size 5 mg
Price $385.00

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Synonym: SPDP-DSPE, 1,2-distearoyl-sn-glycerol-phospho-ethanolamine SPDP

Product Specification:

  • Appearance: Solid;
  • Color: white;
  • Lipid type: C18 saturated phospholipid;
  • Functional group: Pyridyl disulfide;
  • Reactive to: Sulfhydryl group;

Storage:

  • Store at -20 0C; 

Other Products:

DSPE-NHS, DSPE-Biotin, DSPE-PEG, DSPE-FITC, DSPE-Pyrene

SPDP，CAS #: 68181-17-9偶连带活性基团的蛋白示意图

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SPDP，CAS #: 68181-17-9 产品可以偶连带氨基的蛋白和巯基或马来酰亚胺的蛋白，偶连带活性基团的蛋白示意图:

SPDP，CAS #: 68181-17-9偶连带活性基团的蛋白示意图

我们可以提供三种不同结构的SPDP异端功能蛋白交联剂：SPDP,LC-SPDP,Sulfo-LC-SPDP

其中SPDP,LC-SPDP是脂溶性蛋白交联剂，Sulfo-LC-SPDP是水溶性蛋白交联剂。